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NCT03422302 · ClinicalTrials.gov registry record · NA
Continuous Positive Airway Pressure Device or Deep Inspiration Breath Hold in Reducing Tumor Motion in Patients Undergoing Stereotactic Body Radiation Therapy for Lung Cancer
A NA study of Lung Carcinoma and Metastatic Malignant Neoplasm in the Lung, sponsored by M.D. Anderson Cancer Center.
- Recruiting
- Registry status
- NA
- Development phase
- 30
- Enrollment target
- 1
- Study location
NCT03422302: Recruiting NA study of Lung Carcinoma and Metastatic Malignant Neoplasm in the Lung, sponsored by M.D. Anderson Cancer Center.
NCT03422302 is a NA study of Lung Carcinoma and Metastatic Malignant Neoplasm in the Lung that is actively recruiting participants, run by M.D. Anderson Cancer Center. The registered enrollment target is 30 participants, below the 5,043-participant average among 38 other Lung Carcinoma trials with a reported enrollment target (99% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03422302, a NA study of Lung Carcinoma and Metastatic Malignant Neoplasm in the Lung, is actively recruiting participants, sponsored by M.D. Anderson Cancer Center.
- RECRUITING
- Registry status
- NA
- Development phase
- 30 participants
- Enrollment target
- 1
- Study location
Study Summary
This pilot phase I/II trial studies how well a continuous positive airway pressure device or deep inspiration breath hold works in reducing tumor movement in patients undergoing stereotactic body radiation therapy (SBRT) for lung cancer. The continuous positive airway pressure device works by blowing air into the lungs while patients wear a face mask or nozzle to help expand their airways and lungs. Deep inspiration breath hold is a standard technique that uses active breath-holding to restrict movement of the body. Using a continuous positive airway pressure device may work better than deep inspiration breath hold in lowering the amount of tumor movement during stereotactic radiation body therapy.
Primary Outcome
Paired t-test will be used to compare continuous positive airway pressure (CPAP) to deep inspiration breath hold (DIBH) in the decrease of tumor motion from free breathing. Linear regression may be used to evaluate the difference between CPAP and DIBH in the decrease of tumor motion from free breathing with the adjustment of important demographic and clinical variables in the model.
Conditions Studied
Interventions
- PROCEDURE Computed Tomography
- DEVICE Biphasic Positive Airway Pressure
- PROCEDURE Continuous Positive Airway Pressure
- PROCEDURE Deep Inspiration Breath Hold
- RADIATION Radiation Therapy Treatment Planning and Simulation
Study Locations (1)
Texas
- M D Anderson Cancer Center - Houston
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 30 participants |
| Start Date | 2018-03-16 |
| Est. Completion | 2028-05-31 |
| Phase | NA |
What NCT03422302 shows while recruiting
NCT03422302 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 30 participants, a relatively small participant target, below the 5,043-participant average among 38 other Lung Carcinoma trials with a reported enrollment target (99% lower).
The record links to 3 conditions, with Lung Carcinoma appearing as the primary indexed condition, and to 5 interventions - of which Computed Tomography is the first listed.
NCT03422302 reports a single indexed study location in Texas.
Frequently Asked Questions
What is clinical trial NCT03422302 about?
NCT03422302 is a clinical study titled "Continuous Positive Airway Pressure Device or Deep Inspiration Breath Hold in Reducing Tumor Motion in Patients Undergoing Stereotactic Body Radiation Therapy for Lung Cancer". This pilot phase I/II trial studies how well a continuous positive airway pressure device or deep inspiration breath hold works in reducing tumor movement in patients undergoing stereotactic body radiation therapy (SBRT) for lung cancer. The continuous positive airway pressure device works by blowin...
What is the current status of trial NCT03422302?
This trial is currently recruiting. It is a NA study. The enrollment target is 30 participants. The study started on 2018-03-16. Estimated completion is 2028-05-31.
What conditions does trial NCT03422302 study?
This clinical trial studies the following conditions: Lung Carcinoma, Metastatic Malignant Neoplasm in the Lung, Malignant Respiratory Tract Neoplasm.
What interventions are being tested in trial NCT03422302?
The interventions under investigation include: Computed Tomography (PROCEDURE), Biphasic Positive Airway Pressure (DEVICE), Continuous Positive Airway Pressure (PROCEDURE), Deep Inspiration Breath Hold (PROCEDURE), Radiation Therapy Treatment Planning and Simulation (RADIATION).
Who is sponsoring clinical trial NCT03422302?
This trial is sponsored by M.D. Anderson Cancer Center, which has 2,692 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT03422302 being conducted?
This trial has 1 study location across Texas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Where NCT03422302's enrollment target sits among peer trials
30 32nd of 38 higher than 6 of 38 other Lung Carcinoma trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Lung Carcinoma trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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