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NCT03281538 · ClinicalTrials.gov registry record · Phase 3

Extension Study to Evaluate IV CR845 in Hemodialysis Patients With Moderate-to-Severe Pruritus

A Phase 3 study of Uremic Pruritus, sponsored by Cara Therapeutics.

Completed
Registry status
Phase 3
Development phase
288
Enrollment target
20
Study locations

NCT03281538 is a Phase 3 study of Uremic Pruritus that has completed, run by Cara Therapeutics. The registered enrollment target is 288 participants. The trial reports 20 study locations across 12 states.

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The verdict

NCT03281538, a Phase 3 study of Uremic Pruritus, has completed, sponsored by Cara Therapeutics.

COMPLETED
Registry status
Phase 3
Development phase
288 participants
Enrollment target
20
Study locations

Study Summary

This is an open-label multicenter, long-term extension safety study to evaluate the safety of IV CR845 administered after each dialysis session over a Treatment Period of up to 52 weeks.

Conditions Studied

Interventions

  • DRUG CR845

Study Locations (20)

California

  • Cara Therapeutics Study Site - Chula Vista
  • Cara Therapeutics Study Site - El Centro
  • Cara Therapeutics Study Site - Long Beach
  • Cara Therapeutics Study Site - Northridge

Florida

  • Cara Therapeutics Study Site - Hollywood
  • Cara Therapeutics Study Site - Tampa
  • Cara Therapeutics Study Site - Winter Park

Georgia

  • Cara Therapeutics Study Site - Albany
  • Cara Therapeutics Study Site - Augusta

New Mexico

  • Cara Therapeutics Study Site - Albuquerque
  • Cara Therapeutics Study Site - Gallup

New York

  • Cara Therapeutics Study Site - Mineola
  • Cara Therapeutics Study Site - Ridgewood

Colorado

  • Cara Therapeutics Study Site - Denver

Idaho

  • Cara Therapeutics Study Site - Meridian

Massachusetts

  • Cara Therapeutics Study Site - Springfield

Trial Details

FieldValue
Enrollment Target 288 participants
Start Date 2017-08-14
Est. Completion 2020-02-11
Phase Phase 3

Sponsor

Cara Therapeutics

23 total trials

What the Registry Record Tells You About NCT03281538

The ClinicalTrials.gov registry entry for NCT03281538 describes a study currently listed as completed, categorized as Phase 3. The registered enrollment target is 288 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Cara Therapeutics, which has 23 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Uremic Pruritus appearing as the primary indexed condition, and to 1 intervention - of which CR845 is the first listed.

NCT03281538 reports 20 study locations spanning 12 distinct geographic areas - top geographies include California, Florida, Georgia.

Frequently Asked Questions

What is clinical trial NCT03281538 about?

NCT03281538 is a clinical study titled "Extension Study to Evaluate IV CR845 in Hemodialysis Patients With Moderate-to-Severe Pruritus". This is an open-label multicenter, long-term extension safety study to evaluate the safety of IV CR845 administered after each dialysis session over a Treatment Period of up to 52 weeks.

What is the current status of trial NCT03281538?

This trial is currently completed. It is a Phase 3 study. The enrollment target is 288 participants. The study started on 2017-08-14. Estimated completion is 2020-02-11.

What conditions does trial NCT03281538 study?

This clinical trial studies the following conditions: Uremic Pruritus.

What interventions are being tested in trial NCT03281538?

The interventions under investigation include: CR845 (DRUG).

Who is sponsoring clinical trial NCT03281538?

This trial is sponsored by Cara Therapeutics, which has 23 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT03281538 being conducted?

This trial has 20 study locations across California, Colorado, Florida, Georgia, Idaho. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

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