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NCT03277768 · ClinicalTrials.gov registry record

Non-Invasive Detection of Tissue Oxygen Deprivation in Premature Infants With Patent Ductus Arteriosus.

A clinical trial of Premature Infant and Patent Ductus Arteriosus, sponsored by University of Florida.

Completed
Registry status
55
Enrollment target
2
Study locations

NCT03277768: Completed study of Premature Infant and Patent Ductus Arteriosus, sponsored by University of Florida.

NCT03277768 is a study of Premature Infant and Patent Ductus Arteriosus that has completed, run by University of Florida. The registered enrollment target is 55 participants, below the 284-participant average among 9 other Premature Infant trials with a reported enrollment target (81% lower). The trial reports 2 study locations across 2 states. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT03277768, a study of Premature Infant and Patent Ductus Arteriosus, has completed, sponsored by University of Florida.

COMPLETED
Registry status
55 participants
Enrollment target
2
Study locations

Study Summary

The proposed research evaluates tissue oxygenation (StO2) as measured by resonance raman spectroscopy (RRS) in premature infants with and without patent ductus arteriosus (PDA). This is a prospective observational study of infants born at \< 30 weeks of gestation. The primary aim of this study is to determine if the difference in pre- and post-ductal StO2 as detected by RRS is more significant in premature infants with PDA in comparison to infants without PDA. The secondary aim of this study is to determine if the difference in pre- and post-ductal StO2 as detected by RRS is more significant in infant who develop serious adverse events.

Primary Outcome

Pre- and post-ductal tissues oxygenation as measured by RRS may be more significant in infants with PDA.

Conditions Studied

Premature Infant Patent Ductus Arteriosus Hemodynamic Instability

Interventions

  • DEVICE Resonance Raman Spectroscopy (RRS)

Study Locations (2)

Florida

  • University of Florida - Gainesville

Massachusetts

  • Boston Children's Hospital - Boston

Trial Details

FieldValue
Enrollment Target 55 participants
Start Date 2015-05-01
Est. Completion 2018-08-23
University of Florida

1,106 total trials

What the finished NCT03277768 record still lists

NCT03277768 is an observational study that tracks outcomes without assigning an intervention. The registry caps enrollment at 55 participants, a relatively small participant target, below the 284-participant average among 9 other Premature Infant trials with a reported enrollment target (81% lower).

The record links to 3 conditions, with Premature Infant appearing as the primary indexed condition, and to 1 intervention - of which Resonance Raman Spectroscopy (RRS) is the first listed.

NCT03277768 reports a single indexed study location in Florida, Massachusetts.

Frequently Asked Questions

What is clinical trial NCT03277768 about?

NCT03277768 is a clinical study titled "Non-Invasive Detection of Tissue Oxygen Deprivation in Premature Infants With Patent Ductus Arteriosus.". The proposed research evaluates tissue oxygenation (StO2) as measured by resonance raman spectroscopy (RRS) in premature infants with and without patent ductus arteriosus (PDA). This is a prospective observational study of infants born at \< 30 weeks of gestation. The primary aim of this study is to...

What is the current status of trial NCT03277768?

This trial is currently completed. The enrollment target is 55 participants. The study started on 2015-05-01. Estimated completion is 2018-08-23.

What conditions does trial NCT03277768 study?

This clinical trial studies the following conditions: Premature Infant, Patent Ductus Arteriosus, Hemodynamic Instability.

What interventions are being tested in trial NCT03277768?

The interventions under investigation include: Resonance Raman Spectroscopy (RRS) (DEVICE).

Who is sponsoring clinical trial NCT03277768?

This trial is sponsored by University of Florida, which has 1,106 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT03277768 being conducted?

This trial has 2 study locations across Florida, Massachusetts. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Learn More About Clinical Trials

Similar trials for Premature Infant

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT03277768's enrollment target sits among peer trials

55 7th of 9 higher than 3 of 9 other Premature Infant trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Premature Infant trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Related registry views

Source: ClinicalTrials.gov NCT03277768, the US trial registry maintained by the National Library of Medicine. NCT03277768 (small enrollment · single site footprint · completed) retrieved and formatted by PlainTrial, see methodology.