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NCT02998710 · ClinicalTrials.gov registry record
Natural History Study of Homocystinuria Caused by Cystathionine Beta-Synthase Deficiency (ACAPPELLA)
A clinical trial of Homocystinuria Due to CBS Deficiency, sponsored by Travere Therapeutics.
- Recruiting
- Registry status
- 150
- Enrollment target
- 11
- Study locations
NCT02998710: Recruiting study of Homocystinuria Due to CBS Deficiency, sponsored by Travere Therapeutics.
NCT02998710 is a study of Homocystinuria Due to CBS Deficiency that is actively recruiting participants, run by Travere Therapeutics. The registered enrollment target is 150 participants. The trial reports 11 study locations across 10 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT02998710, a study of Homocystinuria Due to CBS Deficiency, is actively recruiting participants, sponsored by Travere Therapeutics.
- RECRUITING
- Registry status
- 150 participants
- Enrollment target
- 11
- Study locations
Study Summary
The purpose of the study is to characterize the clinical course of homocystinuria in pediatric and adult patients aged 1 to 65 years under current clinical management practices
Primary Outcome
Changes in total homocysteine levels in micromoles. The met cycle metabolites levels and change from baseline will be summarized using descriptive statistics at each visit.
Conditions Studied
Study Locations (11)
Other
- Travere Investigational Site - Dublin
- Travere Investigational Site - Doha
California
- Travere Investigational Site - Virtual Site - Culver City
Colorado
- Travere Investigational Site (Enrolling 1 to <5 Year-olds Only) - Aurora
District of Columbia
- Travere Investigational Site (Enrolling 1 to <5 Year-olds Only) - Washington D.C.
Georgia
- Travere Investigational Site - Atlanta
Indiana
- Travere Investigational Site - Indianapolis
Massachusetts
- Travere Investigational Site - Boston
Pennsylvania
- Travere Investigational Site (Enrolling 1 to <5 Year-olds Only) - Philadelphia
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 150 participants |
| Start Date | 2017-01 |
| Est. Completion | 2026-08 |
What NCT02998710 shows while recruiting
NCT02998710 is an observational study that tracks outcomes without assigning an intervention. The registered 150 participants enrollment target is mid-sized for trials with a published cap.
The record links to 1 condition, with Homocystinuria Due to CBS Deficiency appearing as the primary indexed condition, and to 0 interventions.
NCT02998710 lists 11 locations in 10 states (Other, California, Colorado).
Frequently Asked Questions
What is clinical trial NCT02998710 about?
NCT02998710 is a clinical study titled "Natural History Study of Homocystinuria Caused by Cystathionine Beta-Synthase Deficiency (ACAPPELLA)". The purpose of the study is to characterize the clinical course of homocystinuria in pediatric and adult patients aged 1 to 65 years under current clinical management practices
What is the current status of trial NCT02998710?
This trial is currently recruiting. The enrollment target is 150 participants. The study started on 2017-01. Estimated completion is 2026-08.
What conditions does trial NCT02998710 study?
This clinical trial studies the following conditions: Homocystinuria Due to CBS Deficiency.
Who is sponsoring clinical trial NCT02998710?
This trial is sponsored by Travere Therapeutics, which has 12 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT02998710 being conducted?
This trial has 11 study locations across California, Colorado, District of Columbia, Georgia, Indiana. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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