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COMPLETED Phase 1

Modified Measles Virus (MV-NIS) for Children and Young Adults With Recurrent Medulloblastoma or Recurrent ATRT

NCT02962167 · View on ClinicalTrials.gov ↗

Study Summary

This is a three arm Phase I study within the Pacific Pediatric Neuro-Oncology Consortium (PNOC). This study will look to determine the safety and recommended phase 2 dose of the modified measles virus (MV-NIS) in children and young adults with recurrent medulloblastoma or atypical teratoid rhabdoid tumor (ATRT).

Interventions

  • BIOLOGICAL Modified Measles Virus
  • BIOLOGICAL Modified Measles Virus Lumbar Puncture

Study Locations (8)

California

  • Children's Hospital Los Angeles — Los Angeles
  • University of California, San Francisco — San Francisco

Illinois

  • Ann & Robert H. Lurie Children's Hospital of Chicago — Chicago

Missouri

  • Washington University in St. Louis — St Louis

Ohio

  • Nationwide Children's Hospital — Columbus

Pennsylvania

  • Children's Hospital of Philadelphia — Philadelphia

Utah

  • University of Utah — Salt Lake City

Washington

  • Seattle Children's Hospital — Seattle

Trial Details

FieldValue
Enrollment Target 34 participants
Start Date 2017-02-22
Est. Completion 2023-05-10
Phase Phase 1

Sponsor

Sabine Mueller, MD, PhD

6 total trials

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT02962167

The ClinicalTrials.gov registry entry for NCT02962167 describes a study currently listed as completed. It is categorized as Phase 1, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 34 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Sabine Mueller, MD, PhD, which has 6 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.

The record links to 3 conditions, with Atypical Teratoid/Rhabdoid Tumor appearing as the primary indexed condition, and to 2 interventions — of which Modified Measles Virus is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.

Geographic footprint matters for practical reasons: NCT02962167 reports 8 study locations spanning 7 distinct geographic areas — top geographies include California, Illinois, Missouri. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.

Frequently Asked Questions

What is clinical trial NCT02962167 about?

NCT02962167 is a clinical study titled "Modified Measles Virus (MV-NIS) for Children and Young Adults With Recurrent Medulloblastoma or Recurrent ATRT". This is a three arm Phase I study within the Pacific Pediatric Neuro-Oncology Consortium (PNOC). This study will look to determine the safety and recommended phase 2 dose of the modified measles virus (MV-NIS) in children and young adults with recurrent medulloblastoma or atypical teratoid rhabdoid...

What is the current status of trial NCT02962167?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 34 participants. The study started on 2017-02-22. Estimated completion is 2023-05-10.

What conditions does trial NCT02962167 study?

This clinical trial studies the following conditions: Atypical Teratoid/Rhabdoid Tumor, Medulloblastoma Recurrent, Medulloblastoma, Childhood, Recurrent. These conditions were identified from the trial registry and reflect the primary focus areas of the research.

What interventions are being tested in trial NCT02962167?

The interventions under investigation include: Modified Measles Virus (BIOLOGICAL), Modified Measles Virus Lumbar Puncture (BIOLOGICAL). Each intervention is being evaluated for safety and efficacy as part of this clinical study.

Who is sponsoring clinical trial NCT02962167?

This trial is sponsored by Sabine Mueller, MD, PhD, which has 6 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.

Where is trial NCT02962167 being conducted?

This trial has 8 study locations across California, Illinois, Missouri, Ohio, Pennsylvania. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial