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NCT02745626 · ClinicalTrials.gov registry record · NA
Comparison of Oral Hygiene & Root Resorption During Orthodontic Treatment
A NA study of Orthodontic Pathological Resorption of External Root and Complication of Personal Oral Hygiene, sponsored by UConn Health.
- Completed
- Registry status
- NA
- Development phase
- 68
- Enrollment target
- 1
- Study location
NCT02745626 is a NA study of Orthodontic Pathological Resorption of External Root and Complication of Personal Oral Hygiene that has completed, run by UConn Health. The registered enrollment target is 68 participants. The trial reports 1 study location across 1 state.
The verdict
NCT02745626, a NA study of Orthodontic Pathological Resorption of External Root and Complication of Personal Oral Hygiene, has completed, sponsored by UConn Health.
- COMPLETED
- Registry status
- NA
- Development phase
- 68 participants
- Enrollment target
- 1
- Study location
Study Summary
Orthodontic treatment has been traditionally carried out with fixed appliances involving the use of stainless steel brackets and archwires. The challenge has been to move teeth and their roots effectively while minimizing iatrogenic damage such as root resorption and gingival inflammation. In recent years, with the development of new appliances and brackets such as self-ligating brackets and clear aligners there have been reports of improved periodontal status, less iatrogenic root damage and improved hygiene during treatment. Although these treatment modalities have been rapidly accepted in clinical practice, both clinical and basic science research data regarding their overall biological compatibility to support higher levels of evidence based dentistry (e.g, randomized clinical trials) is lacking. In other words, their advantages and disadvantages in this regard have not yet been scientifically evaluated. Such quantification will provide invaluable information for improvements in these treatment modalities. A randomized controlled clinical trial will be conducted with strict inclusion and exclusion criteria to test the following hypothesis (H) up to 18 months into treatment: H-1: There is no difference in the amount of root resorption caused by the three different appliances. H-2: Gingival health is not affected by the 'type of appliance' being used to correct the malocclusion. H-3: There is no difference in the amount of bacterial count and the type of appliance being used for orthodontic treatment. The hypothesis will be tested with the following specific aims (SA): SA-1: To investigate the amount of orthodontically induced inflammatory root resorption generated by treatment. SA-2: To evaluate the periodontal health of the patients with the different appliance systems. SA-3: To determine the changes in Streptococcus mutans and total bacterial counts contained in the plaque of orthodontic patients. SA-4: To ascertain whether there is an association betw
Conditions Studied
Interventions
- DEVICE Appliance
Study Locations (1)
Connecticut
- Orthodontic Center at University of Connecticut Health Center - Farmington
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 68 participants |
| Start Date | 2011-12 |
| Est. Completion | 2015-11 |
| Phase | NA |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT02745626
The ClinicalTrials.gov registry entry for NCT02745626 describes a study currently listed as completed, categorized as NA. The registered enrollment target is 68 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is UConn Health, which has 178 total studies on file at ClinicalTrials.gov.
The record links to 2 conditions, with Orthodontic Pathological Resorption of External Root appearing as the primary indexed condition, and to 1 intervention - of which Appliance is the first listed.
NCT02745626 reports 1 study location spanning 1 distinct geographic area - top geographies include Connecticut.
Frequently Asked Questions
What is clinical trial NCT02745626 about?
NCT02745626 is a clinical study titled "Comparison of Oral Hygiene & Root Resorption During Orthodontic Treatment". Orthodontic treatment has been traditionally carried out with fixed appliances involving the use of stainless steel brackets and archwires. The challenge has been to move teeth and their roots effectively while minimizing iatrogenic damage such as root resorption and gingival inflammation. In recent...
What is the current status of trial NCT02745626?
This trial is currently completed. It is a NA study. The enrollment target is 68 participants. The study started on 2011-12. Estimated completion is 2015-11.
What conditions does trial NCT02745626 study?
This clinical trial studies the following conditions: Orthodontic Pathological Resorption of External Root, Complication of Personal Oral Hygiene.
What interventions are being tested in trial NCT02745626?
The interventions under investigation include: Appliance (DEVICE).
Who is sponsoring clinical trial NCT02745626?
This trial is sponsored by UConn Health, which has 178 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT02745626 being conducted?
This trial has 1 study location across Connecticut. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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Orthodontic Pathological Resorption of External Root
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