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NCT02745626 · ClinicalTrials.gov registry record · NA
Comparison of Oral Hygiene & Root Resorption During Orthodontic Treatment
A NA study of Orthodontic Pathological Resorption of External Root and Complication of Personal Oral Hygiene, sponsored by UConn Health.
- Completed
- Registry status
- NA
- Development phase
- 68
- Enrollment target
- 1
- Study location
NCT02745626: Completed NA study of Orthodontic Pathological Resorption of External Root and Complication of Personal Oral Hygiene, sponsored by UConn Health.
NCT02745626 is a NA study of Orthodontic Pathological Resorption of External Root and Complication of Personal Oral Hygiene that has completed, run by UConn Health. The registered enrollment target is 68 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (95% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT02745626, a NA study of Orthodontic Pathological Resorption of External Root and Complication of Personal Oral Hygiene, has completed, sponsored by UConn Health.
- COMPLETED
- Registry status
- NA
- Development phase
- 68 participants
- Enrollment target
- 1
- Study location
Study Summary
Orthodontic treatment has been traditionally carried out with fixed appliances involving the use of stainless steel brackets and archwires. The challenge has been to move teeth and their roots effectively while minimizing iatrogenic damage such as root resorption and gingival inflammation. In recent years, with the development of new appliances and brackets such as self-ligating brackets and clear aligners there have been reports of improved periodontal status, less iatrogenic root damage and improved hygiene during treatment. Although these treatment modalities have been rapidly accepted in clinical practice, both clinical and basic science research data regarding their overall biological compatibility to support higher levels of evidence based dentistry (e.g, randomized clinical trials) is lacking. In other words, their advantages and disadvantages in this regard have not yet been scientifically evaluated. Such quantification will provide invaluable information for improvements in these treatment modalities. A randomized controlled clinical trial will be conducted with strict inclusion and exclusion criteria to test the following hypothesis (H) up to 18 months into treatment: H-1: There is no difference in the amount of root resorption caused by the three different appliances. H-2: Gingival health is not affected by the 'type of appliance' being used to correct the malocclusion. H-3: There is no difference in the amount of bacterial count and the type of appliance being used for orthodontic treatment. The hypothesis will be tested with the following specific aims (SA): SA-1: To investigate the amount of orthodontically induced inflammatory root resorption generated by treatment. SA-2: To evaluate the periodontal health of the patients with the different appliance systems. SA-3: To determine the changes in Streptococcus mutans and total bacterial counts contained in the plaque of orthodontic patients. SA-4: To ascertain whether there is an association betw
Primary Outcome
A measure of the plaque levels on the desired tooth surface. The following scores were used: 0 no plaque/debris on inspection and probing 1. thin film of plaque only visible after probing 2. ribbon-like layer of plaque covering the sulcus \& gingival crown areas but not filling interdental space 3. thick layer of plaque already visible at inspection and filling interdental space
Conditions Studied
Interventions
- DEVICE Appliance
Study Locations (1)
Connecticut
- Orthodontic Center at University of Connecticut Health Center - Farmington
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 68 participants |
| Start Date | 2011-12 |
| Est. Completion | 2015-11 |
| Phase | NA |
What the finished NCT02745626 record still lists
NCT02745626 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 68 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (95% lower).
The record links to 2 conditions, with Orthodontic Pathological Resorption of External Root appearing as the primary indexed condition, and to 1 intervention - of which Appliance is the first listed.
NCT02745626 reports a single indexed study location in Connecticut.
Frequently Asked Questions
What is clinical trial NCT02745626 about?
NCT02745626 is a clinical study titled "Comparison of Oral Hygiene & Root Resorption During Orthodontic Treatment". Orthodontic treatment has been traditionally carried out with fixed appliances involving the use of stainless steel brackets and archwires. The challenge has been to move teeth and their roots effectively while minimizing iatrogenic damage such as root resorption and gingival inflammation. In recent...
What is the current status of trial NCT02745626?
This trial is currently completed. It is a NA study. The enrollment target is 68 participants. The study started on 2011-12. Estimated completion is 2015-11.
What conditions does trial NCT02745626 study?
This clinical trial studies the following conditions: Orthodontic Pathological Resorption of External Root, Complication of Personal Oral Hygiene.
What interventions are being tested in trial NCT02745626?
The interventions under investigation include: Appliance (DEVICE).
Who is sponsoring clinical trial NCT02745626?
This trial is sponsored by UConn Health, which has 178 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT02745626 being conducted?
This trial has 1 study location across Connecticut. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT02745626's enrollment target sits among peer trials
68 1133rd of 2000 higher than 862 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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