Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
Direct Oral Anticoagulants (DOACs) Versus LMWH +/- Warfarin for VTE in Cancer
NCT02744092 · View on ClinicalTrials.gov ↗
Study Summary
The overarching objective of the study is to determine the effectiveness of LMWH/ warfarin vs. DOAC anticoagulation for preventing recurrent VTE in cancer patients. The intervention strategy is Direct Oral AntiCoagulants (DOAC) therapy with edoxaban, apixaban, rivaroxaban, or dabigatran. The comparator is low molecular weight heparin (LMWH) alone or with warfarin. The information gained will empower cancer patients and physicians to make more informed choices about anticoagulation strategies to manage VTE.
Conditions Studied
Interventions
- DRUG Apixaban
- DRUG Warfarin
- DRUG Rivaroxaban
- DRUG Edoxaban
- DRUG Dabigatran
Study Locations (20)
California
- South County Hematology — Chula Vista
- Sharp Rees-Stealy — Chula Vista
- Washington Hospital Healthcare System — Fremont
- Washington Hospital — Fremont
- VA Central California Fresno Medical Center — Fresno
- Cancer Center Oncology Medical Group — La Mesa
- Medical Oncology Associates- San Diego — San Diego
- Sharp Memorial Hospital — San Diego
- Sharp Rees-Stealy — San Diego
- UCSF Medical Center - Mission Bay — San Francisco
- Saint Joseph's Medical Center — Stockton
Florida
- Morton Plant Hospital — Clearwater
- Breast Cancer Center at Memorial Regional Hospital — Hollywood
- Memorial Cancer Institute at Memorial Regional Hospital — Hollywood
- Memorial Regional Hospital — Hollywood
- Hollis Cancer Center — Lakeland
- Breast Cancer Center at Memorial Hospital West — Pembroke Pines
- Memorial Cancer Institute at Memorial Hospital West — Pembroke Pines
Connecticut
- Middlesex Hospital — Middletown
- The Stamford Hospital — Stamford
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 811 participants |
| Start Date | 2016-12-13 |
| Est. Completion | 2021-02-22 |
| Phase | NA |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT02744092
The ClinicalTrials.gov registry entry for NCT02744092 describes a study currently listed as completed. It is categorized as NA, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 811 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Alliance Foundation Trials, which has 71 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.
The record links to 5 conditions, with Cancer appearing as the primary indexed condition, and to 5 interventions — of which Apixaban is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.
Geographic footprint matters for practical reasons: NCT02744092 reports 20 study locations spanning 3 distinct geographic areas — top geographies include California, Florida, Connecticut. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.
Frequently Asked Questions
What is clinical trial NCT02744092 about?
NCT02744092 is a clinical study titled "Direct Oral Anticoagulants (DOACs) Versus LMWH +/- Warfarin for VTE in Cancer". The overarching objective of the study is to determine the effectiveness of LMWH/ warfarin vs. DOAC anticoagulation for preventing recurrent VTE in cancer patients. The intervention strategy is Direct Oral AntiCoagulants (DOAC) therapy with edoxaban, apixaban, rivaroxaban, or dabigatran. The compara...
What is the current status of trial NCT02744092?
This trial is currently completed. It is a NA study. The enrollment target is 811 participants. The study started on 2016-12-13. Estimated completion is 2021-02-22.
What conditions does trial NCT02744092 study?
This clinical trial studies the following conditions: Cancer, Venous Thromboembolism, Deep Vein Thrombosis (DVT), Pulmonary Embolism (PE), Blood Clot. These conditions were identified from the trial registry and reflect the primary focus areas of the research.
What interventions are being tested in trial NCT02744092?
The interventions under investigation include: Apixaban (DRUG), Warfarin (DRUG), Rivaroxaban (DRUG), Edoxaban (DRUG), Dabigatran (DRUG). Each intervention is being evaluated for safety and efficacy as part of this clinical study.
Who is sponsoring clinical trial NCT02744092?
This trial is sponsored by Alliance Foundation Trials, which has 71 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.
Where is trial NCT02744092 being conducted?
This trial has 20 study locations across California, Connecticut, Florida. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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