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RECRUITING Phase 3

Randomized, Embedded, Multifactorial Adaptive Platform Trial for Community- Acquired Pneumonia

NCT02735707 · View on ClinicalTrials.gov ↗

Study Summary

REMAP-CAP is a randomised, embedded, multifactorial, adaptive platform trial for community-acquired pneumonia. The purpose of this study is to evaluate the effect of a range of interventions to improve outcome of patients admitted to intensive care with community-acquired pneumonia. In addition, REMAP-CAP provides and adaptive research platform for evaluation of multiple treatment modalities in the event of a respiratory pandemic such as COVID-19. REMAP-COVID is a sub-platform of REMAP-CAP that evaluates treatments specific to COVID-19 in the United States of America.

Interventions

  • DRUG Amoxicillin-clavulanate
  • DRUG Ceftriaxone
  • DRUG Moxifloxacin or Levofloxacin
  • DRUG Piperacillin-tazobactam
  • DRUG Ceftaroline

Study Locations (20)

New South Wales

  • Bankstown-Lidcombe Hospital — Bankstown
  • Blacktown Hospital — Blacktown
  • Campbelltown Hospital — Campbelltown
  • Sutherland Hospital — Caringbah
  • Concord Hospital — Concord
  • Dubbo Base Hospital — Dubbo
  • Northern Beaches Hospital — Frenchs Forest
  • Nepean Hospital — Kingswood

Florida

  • University of Florida — Jacksonville

Georgia

  • Augusta University — Augusta

Illinois

  • University of Illinois Health — Chicago

Louisiana

  • Tulane Medical Center — New Orleans

Michigan

  • University of Michigan — Ann Arbor

New York

  • Memorial Sloan Kettering Cancer Center — New York

North Carolina

  • Wake Forest Baptist Health — Winston-Salem

Trial Details

FieldValue
Enrollment Target 20,000 participants
Start Date 2016-04-11
Est. Completion 2028-02
Phase Phase 3

Sponsor

UMC Utrecht

3 total trials

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT02735707

The ClinicalTrials.gov registry entry for NCT02735707 describes a study currently listed as recruiting. It is categorized as Phase 3, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 20,000 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is UMC Utrecht, which has 3 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.

The record links to 1 condition, with Community-acquired Pneumonia, Influenza, COVID-19 appearing as the primary indexed condition, and to 5 interventions — of which Amoxicillin-clavulanate is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.

Geographic footprint matters for practical reasons: NCT02735707 reports 20 study locations spanning 13 distinct geographic areas — top geographies include New South Wales, Florida, Georgia. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.

Frequently Asked Questions

What is clinical trial NCT02735707 about?

NCT02735707 is a clinical study titled "Randomized, Embedded, Multifactorial Adaptive Platform Trial for Community- Acquired Pneumonia". REMAP-CAP is a randomised, embedded, multifactorial, adaptive platform trial for community-acquired pneumonia. The purpose of this study is to evaluate the effect of a range of interventions to improve outcome of patients admitted to intensive care with community-acquired pneumonia. In addition, R...

What is the current status of trial NCT02735707?

This trial is currently recruiting. It is a Phase 3 study. The enrollment target is 20,000 participants. The study started on 2016-04-11. Estimated completion is 2028-02.

What conditions does trial NCT02735707 study?

This clinical trial studies the following conditions: Community-acquired Pneumonia, Influenza, COVID-19. These conditions were identified from the trial registry and reflect the primary focus areas of the research.

What interventions are being tested in trial NCT02735707?

The interventions under investigation include: Amoxicillin-clavulanate (DRUG), Ceftriaxone (DRUG), Moxifloxacin or Levofloxacin (DRUG), Piperacillin-tazobactam (DRUG), Ceftaroline (DRUG). Each intervention is being evaluated for safety and efficacy as part of this clinical study.

Who is sponsoring clinical trial NCT02735707?

This trial is sponsored by UMC Utrecht, which has 3 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.

Where is trial NCT02735707 being conducted?

This trial has 20 study locations across Florida, Georgia, Illinois, Louisiana, Michigan. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial