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NCT02520258 · ClinicalTrials.gov registry record · NA
Study of the Reversibility of Glucose Intolerance Caused by Chronic Aspartame Consumption
A NA study of Glucose Metabolism Disorder, sponsored by Rockefeller University.
- Completed
- Registry status
- NA
- Development phase
- 75
- Enrollment target
- 1
- Study location
NCT02520258: Completed NA study of Glucose Metabolism Disorder, sponsored by Rockefeller University.
NCT02520258 is a NA study of Glucose Metabolism Disorder that has completed, run by Rockefeller University. The registered enrollment target is 75 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (95% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT02520258, a NA study of Glucose Metabolism Disorder, has completed, sponsored by Rockefeller University.
- COMPLETED
- Registry status
- NA
- Development phase
- 75 participants
- Enrollment target
- 1
- Study location
Study Summary
Experiments have shown that some artificial sweeteners like those in diet soda can cause changes in how the body responds to and uses sugar. These changes increase the chance of obesity, type 2 diabetes, and other metabolic diseases. In this study, the investigators plan to see if the most common artificial sweetener, aspartame (brand name Equal, NutraSweet), causes these changes. The investigators believe that if metabolic changes are observed in a person who consumes aspartame, then removing all aspartame from the diet might lead to a reversal of the changes and a normalization of test results.This would impact sweetener additives in our foods and thus decrease the incidence of obesity, diabetes, and the metabolic syndrome.
Primary Outcome
Phase II (cohort 1): Interval changes in blood glucose will be quantified from area under the curve calculated from oral glucose tolerance tests (OGTT)
Conditions Studied
Interventions
- OTHER Oral glucose tolerance test (OGTT)
- OTHER Diet soda containing aspartame only
Study Locations (1)
New York
- The Rockefeller University - New York
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 75 participants |
| Start Date | 2015-08 |
| Est. Completion | 2019-06-25 |
| Phase | NA |
What the finished NCT02520258 record still lists
NCT02520258 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 75 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (95% lower).
The record links to 1 condition, with Glucose Metabolism Disorder appearing as the primary indexed condition, and to 2 interventions - of which Oral glucose tolerance test (OGTT) is the first listed.
NCT02520258 reports a single indexed study location in New York.
Frequently Asked Questions
What is clinical trial NCT02520258 about?
NCT02520258 is a clinical study titled "Study of the Reversibility of Glucose Intolerance Caused by Chronic Aspartame Consumption". Experiments have shown that some artificial sweeteners like those in diet soda can cause changes in how the body responds to and uses sugar. These changes increase the chance of obesity, type 2 diabetes, and other metabolic diseases. In this study, the investigators plan to see if the most common ar...
What is the current status of trial NCT02520258?
This trial is currently completed. It is a NA study. The enrollment target is 75 participants. The study started on 2015-08. Estimated completion is 2019-06-25.
What conditions does trial NCT02520258 study?
This clinical trial studies the following conditions: Glucose Metabolism Disorder.
What interventions are being tested in trial NCT02520258?
The interventions under investigation include: Oral glucose tolerance test (OGTT) (OTHER), Diet soda containing aspartame only (OTHER).
Who is sponsoring clinical trial NCT02520258?
This trial is sponsored by Rockefeller University, which has 117 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT02520258 being conducted?
This trial has 1 study location across New York. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT02520258's enrollment target sits among peer trials
75 1069th of 2000 higher than 919 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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