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COMPLETED Phase 1

Trial Investigating Safety, Pharmacokinetics and Pharmacodynamics of Concizumab Administered Subcutaneously to Haemophilia A Subjects

NCT02490787 · View on ClinicalTrials.gov ↗

Study Summary

This trial is conducted globally. The aim of this trial is to investigate safety, pharmacokinetics (the exposure of the trial drug in the body) and pharmacodynamics (the effect of the investigated drug on the body) of concizumab administered subcutaneously to haemophilia A subjects.

Interventions

  • DRUG placebo
  • DRUG Concizumab

Study Locations (20)

Other

  • Novo Nordisk Investigational Site — Vienna
  • Novo Nordisk Investigational Site — Zagreb
  • Novo Nordisk Investigational Site — Bron
  • Novo Nordisk Investigational Site — Nantes
  • Novo Nordisk Investigational Site — Rennes
  • Novo Nordisk Investigational Site — Berlin
  • Novo Nordisk Investigational Site — Duisburg
  • Novo Nordisk Investigational Site — Homburg
  • Novo Nordisk Investigational Site — Tel Litwinsky
  • Novo Nordisk Investigational Site — Kuala Lumpur

California

  • Novo Nordisk Investigational Site — Torrance

Indiana

  • Novo Nordisk Investigational Site — Indianapolis

Iowa

  • Novo Nordisk Investigational Site — Iowa City

Maryland

  • Novo Nordisk Investigational Site — Baltimore

New York

  • Novo Nordisk Investigational Site — New York

Oregon

  • Novo Nordisk Investigational Site — Portland

Texas

  • Novo Nordisk Investigational Site — Houston

Trial Details

FieldValue
Enrollment Target 24 participants
Start Date 2015-09-10
Est. Completion 2016-10-14
Phase Phase 1

Sponsor

Novo Nordisk A/S

189 total trials

Interested in This Trial?

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT02490787

The ClinicalTrials.gov registry entry for NCT02490787 describes a study currently listed as completed. It is categorized as Phase 1, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 24 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Novo Nordisk A/S, which has 189 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.

The record links to 2 conditions, with Haemophilia A appearing as the primary indexed condition, and to 2 interventions — of which placebo is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.

Geographic footprint matters for practical reasons: NCT02490787 reports 20 study locations spanning 11 distinct geographic areas — top geographies include Other, California, Indiana. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.

Frequently Asked Questions

What is clinical trial NCT02490787 about?

NCT02490787 is a clinical study titled "Trial Investigating Safety, Pharmacokinetics and Pharmacodynamics of Concizumab Administered Subcutaneously to Haemophilia A Subjects". This trial is conducted globally. The aim of this trial is to investigate safety, pharmacokinetics (the exposure of the trial drug in the body) and pharmacodynamics (the effect of the investigated drug on the body) of concizumab administered subcutaneously to haemophilia A subjects.

What is the current status of trial NCT02490787?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 24 participants. The study started on 2015-09-10. Estimated completion is 2016-10-14.

What conditions does trial NCT02490787 study?

This clinical trial studies the following conditions: Haemophilia A, Congenital Bleeding Disorder. These conditions were identified from the trial registry and reflect the primary focus areas of the research.

What interventions are being tested in trial NCT02490787?

The interventions under investigation include: placebo (DRUG), Concizumab (DRUG). Each intervention is being evaluated for safety and efficacy as part of this clinical study.

Who is sponsoring clinical trial NCT02490787?

This trial is sponsored by Novo Nordisk A/S, which has 189 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.

Where is trial NCT02490787 being conducted?

This trial has 20 study locations across California, Indiana, Iowa, Maryland, New York. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial