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Preservation of Ovarian Tissue and Chemo-Radiotherapy
NCT02429349 · View on ClinicalTrials.gov ↗
Study Summary
The purpose of this study is to assess the results of ovarian tissue freezing, such as resumption or initiation of menses (menstruation: the discharge of blood and tissue from the uterus that happens about every 4 weeks in females who are not pregnant) and pregnancy, prior to starting chemotherapy or radiation treatment (commonly used for cancer treatment or for other conditions such as multiple sclerosis, psoriasis, rheumatoid arthritis). Females who are about to undergo chemotherapy or radiation therapy for cancer or these other medical conditions may stop having menses and may not be able to produce a biological child. Girls who have not achieved puberty and are exposed to chemotherapy (alkylating agents) or radiation treatment, the risk is up to 22-50%. In contrast, girls older than 10 years, or who have achieved puberty, experience acute ovarian failure in over 50% of the cases. By freezing and preserving ovarian tissue will help prevent these outcomes. In fact, when you are considered cured of your disease, you will have another surgical procedure where your own ovarian tissue will be transplanted back to you. This surgery will increase the possibility of resuming/initiating menses and the chance to have a pregnancy.
Conditions Studied
Interventions
- PROCEDURE surgery
Study Locations (7)
Tennessee
- Methodist/LeBonheur Hospital — Germantown
- LeBonheur Children's Hospital — Memphis
- Regional One Health Ob-Gyn Clinic — Memphis
- Regional One Health, Regional Medical Center, Operating Room — Memphis
- Methodist University Hospital — Memphis
- St. Jude Children's Research Hospital — Memphis
- Baptist Memorial Hospital — Memphis
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 2 participants |
| Start Date | 2015-05 |
| Est. Completion | 2020-06-30 |
| Phase | NA |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT02429349
The ClinicalTrials.gov registry entry for NCT02429349 describes a study currently listed as completed. It is categorized as NA, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 2 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is University of Tennessee, which has 58 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.
The record links to 3 conditions, with Endocrine Disorders of Female Reproductive System appearing as the primary indexed condition, and to 1 intervention — of which surgery is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.
Geographic footprint matters for practical reasons: NCT02429349 reports 7 study locations spanning 1 distinct geographic area — top geographies include Tennessee. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.
Frequently Asked Questions
What is clinical trial NCT02429349 about?
NCT02429349 is a clinical study titled "Preservation of Ovarian Tissue and Chemo-Radiotherapy". The purpose of this study is to assess the results of ovarian tissue freezing, such as resumption or initiation of menses (menstruation: the discharge of blood and tissue from the uterus that happens about every 4 weeks in females who are not pregnant) and pregnancy, prior to starting chemotherapy o...
What is the current status of trial NCT02429349?
This trial is currently completed. It is a NA study. The enrollment target is 2 participants. The study started on 2015-05. Estimated completion is 2020-06-30.
What conditions does trial NCT02429349 study?
This clinical trial studies the following conditions: Endocrine Disorders of Female Reproductive System, Secondary Infertility, Infertility Involuntary. These conditions were identified from the trial registry and reflect the primary focus areas of the research.
What interventions are being tested in trial NCT02429349?
The interventions under investigation include: surgery (PROCEDURE). Each intervention is being evaluated for safety and efficacy as part of this clinical study.
Who is sponsoring clinical trial NCT02429349?
This trial is sponsored by University of Tennessee, which has 58 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.
Where is trial NCT02429349 being conducted?
This trial has 7 study locations across Tennessee. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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