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NCT02370875 · ClinicalTrials.gov registry record · NA

rTMS and Botulinum Toxin in Benign Essential Blepharospasm

A NA study of Benign Essential Blepharospasm, sponsored by University of Florida.

Completed
Registry status
NA
Development phase
12
Enrollment target
1
Study location

NCT02370875: Completed NA study of Benign Essential Blepharospasm, sponsored by University of Florida.

NCT02370875 is a NA study of Benign Essential Blepharospasm that has completed, run by University of Florida. The registered enrollment target is 12 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (99% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT02370875, a NA study of Benign Essential Blepharospasm, has completed, sponsored by University of Florida.

COMPLETED
Registry status
NA
Development phase
12 participants
Enrollment target
1
Study location

Study Summary

Benign essential blepharospasm (BEB) is a functionally disabling focal dystonia. Botulinum neurotoxin (BoNT) therapy is suboptimal in many BEB patients. Repetitious transcranial magnetic stimulation (rTMS) therapy is a promising noninvasive therapy and has shown positive benefits in BEB. rTMS therapy can be easily combined with BoNT injections to enhance the effects of BoNT in BEB.

Primary Outcome

The change in the score of the Jankovic Rating Scale subscore for severity. Rated on a 5-point scale (0-4), where a higher score indicates higher severity of blepharospasm.

Interventions

  • DEVICE Magstim RapidStim2
  • DEVICE Sham Magstim RapidStim2

Study Locations (1)

Florida

  • Center for Movement Disorders and Neurorestoration - Gainesville

Trial Details

FieldValue
Enrollment Target 12 participants
Start Date 2015-02
Est. Completion 2017-11
Phase NA
University of Florida

1,106 total trials

What the finished NCT02370875 record still lists

NCT02370875 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 12 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (99% lower).

The record links to 1 condition, with Benign Essential Blepharospasm appearing as the primary indexed condition, and to 2 interventions - of which Magstim RapidStim2 is the first listed.

NCT02370875 reports a single indexed study location in Florida.

Frequently Asked Questions

What is clinical trial NCT02370875 about?

NCT02370875 is a clinical study titled "rTMS and Botulinum Toxin in Benign Essential Blepharospasm". Benign essential blepharospasm (BEB) is a functionally disabling focal dystonia. Botulinum neurotoxin (BoNT) therapy is suboptimal in many BEB patients. Repetitious transcranial magnetic stimulation (rTMS) therapy is a promising noninvasive therapy and has shown positive benefits in BEB. rTMS therap...

What is the current status of trial NCT02370875?

This trial is currently completed. It is a NA study. The enrollment target is 12 participants. The study started on 2015-02. Estimated completion is 2017-11.

What conditions does trial NCT02370875 study?

This clinical trial studies the following conditions: Benign Essential Blepharospasm.

What interventions are being tested in trial NCT02370875?

The interventions under investigation include: Magstim RapidStim2 (DEVICE), Sham Magstim RapidStim2 (DEVICE).

Who is sponsoring clinical trial NCT02370875?

This trial is sponsored by University of Florida, which has 1,106 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT02370875 being conducted?

This trial has 1 study location across Florida. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Similar trials for Benign Essential Blepharospasm

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT02370875's enrollment target sits among peer trials

12 1913th of 2000 higher than 74 of 2,000 other NA trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT02370875, the US trial registry maintained by the National Library of Medicine. NCT02370875 (small enrollment · single site footprint · completed) retrieved and formatted by PlainTrial, see methodology.