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NCT02198261 · ClinicalTrials.gov registry record
Minoxidil Response Testing in Males With Androgenetic Alopecia
A clinical trial of Androgenetic Alopecia, sponsored by Applied Biology.
- Completed
- Registry status
- 300
- Enrollment target
- 5
- Study locations
NCT02198261 is a study of Androgenetic Alopecia that has completed, run by Applied Biology. The registered enrollment target is 300 participants, above the 146-participant average among 16 other Androgenetic Alopecia trials with a reported enrollment target (105% higher). The trial reports 5 study locations across 3 states.
The verdict
NCT02198261, a study of Androgenetic Alopecia, has completed, sponsored by Applied Biology.
- COMPLETED
- Registry status
- 300 participants
- Enrollment target
- 5
- Study locations
Study Summary
Topical minoxidil is the most common drug used for the treatment of AGA in men. While topical minoxidil exhibits a good safety profile, the efficacy in the overall population remains relatively low i.e., 30-40% re-grow hair. To observe significant improvement in hair growth, minoxidil is typically used twice daily for a period of at least 16 weeks. Due to the significant time commitment and low response rate, a diagnostic test to identify non-responders prior to initiating therapy would be advantageous. Minoxidil is converted in the scalp to its active form, minoxidil sulfate, by the sulfotransferase enzyme SULT1A1. The enzyme expression is variable among individuals. We have demonstrated in two prior feasibility studies that the SULT1A1 enzyme activity in plucked hair follicles correlates with minoxidil response in the treatment of AGA and thus can server as a predictive biomarker. Consequently, we developed a minoxidil response in-vitro diagnostic kit intended to identify non-responders prior to initiating therapy with 5% topical minoxidil foam. The primary purpose of this study is to evaluate the clinical validity of the minoxidil response in-vitro diagnostic kit.
Conditions Studied
Interventions
- DRUG 5% minoxidil topical foam
Study Locations (5)
Other
- Sinclair Dermatology - East Melbourne
- LTM Medical College & Hospital - Mumbai
- Istituto Medico Tricologico/Studi Life Cronos - Florence
Arizona
- Physicians Hair Institute - Tucson
Tennessee
- Tennessee Clinical Research Center - Nashville
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 300 participants |
| Start Date | 2014-07 |
| Est. Completion | 2018-10 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT02198261
The ClinicalTrials.gov registry entry for NCT02198261 describes a study currently listed as completed, categorized as an unspecified phase. The registered enrollment target is 300 participants, a figure that helps gauge the scale of data the investigators plan to collect, above the 146-participant average among 16 other Androgenetic Alopecia trials with a reported enrollment target (105% higher). The listed sponsor is Applied Biology, which has 6 total studies on file at ClinicalTrials.gov.
The record links to 1 condition, with Androgenetic Alopecia appearing as the primary indexed condition, and to 1 intervention - of which 5% minoxidil topical foam is the first listed.
NCT02198261 reports 5 study locations spanning 3 distinct geographic areas - top geographies include Other, Arizona, Tennessee.
Frequently Asked Questions
What is clinical trial NCT02198261 about?
NCT02198261 is a clinical study titled "Minoxidil Response Testing in Males With Androgenetic Alopecia". Topical minoxidil is the most common drug used for the treatment of AGA in men. While topical minoxidil exhibits a good safety profile, the efficacy in the overall population remains relatively low i.e., 30-40% re-grow hair. To observe significant improvement in hair growth, minoxidil is typically u...
What is the current status of trial NCT02198261?
This trial is currently completed. The enrollment target is 300 participants. The study started on 2014-07. Estimated completion is 2018-10.
What conditions does trial NCT02198261 study?
This clinical trial studies the following conditions: Androgenetic Alopecia.
What interventions are being tested in trial NCT02198261?
The interventions under investigation include: 5% minoxidil topical foam (DRUG).
Who is sponsoring clinical trial NCT02198261?
This trial is sponsored by Applied Biology, which has 6 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT02198261 being conducted?
This trial has 5 study locations across Arizona, Tennessee. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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Read our methodology - how this data is sourced, computed, and verified.
Related
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