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NCT01793779 · ClinicalTrials.gov registry record · NA
Comparison of Pre-exercise Beta-hydroxy-beta-methylbutyrate Free Acid (HMB-FA) and Cold Water Therapy for the Attenuation of Muscle Damage and Soreness
A NA study of Muscle Damage, sponsored by Metabolic Technologies.
- Completed
- Registry status
- NA
- Development phase
- 40
- Enrollment target
- 1
- Study location
NCT01793779: Completed NA study of Muscle Damage, sponsored by Metabolic Technologies.
NCT01793779 is a NA study of Muscle Damage that has completed, run by Metabolic Technologies. The registered enrollment target is 40 participants, roughly in line with the 38-participant average among 6 other Muscle Damage trials with a reported enrollment target. The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01793779, a NA study of Muscle Damage, has completed, sponsored by Metabolic Technologies.
- COMPLETED
- Registry status
- NA
- Development phase
- 40 participants
- Enrollment target
- 1
- Study location
Study Summary
Study Objectives 1. Compare beta-hydroxy-beta-methylbutyrate free acid (HMB-FA) to cold water immersion on performance recovery from an acute bout of high intensity resistance exercise. 2. Compare HMB-FA + Cold water immersion to HMB-FA or cold water immersion. 3. Examine the effect of these recovery modalities on markers of muscle damage, inflammation and immune function. Subjects Subjects (men and women, 18 - 35 y) with at least one year of resistance training experience will be recruited. Subjects will be randomly divided into one of four groups: a cold water immersion group (CW), HMB-FA, CW+HMB-FA and a control group (CT). Study Protocol Subjects will report to the Human Performance Laboratory (HPL) on four separate occasions. On the first visit (T1) subjects will be tested for maximal strength \[one repetition-maximum (1-RM)\] on the squat, dead lift and barbell lunge exercises.\] On their second visit (T2) subjects will perform a lower body resistance exercise session consisting of four sets of the squat, dead lift and barbell lunge exercises. All subjects will then report back to the HPL at 24- (T3) and 48-hours (T4) post-exercise. During T3 and T4, subjects will perform four sets of the squat exercise only using the same loading pattern and rest interval length as T2. Following the T2 and T3 workouts subjects in CT will undergo no treatment; subjects in CW will be required to sit in a whirlpool tub for 10-min up to their umbilicus in water at 50° F - 54° F (10° C - 12° C); subjects in HMB-FA will be provided the supplement 30 min prior each workout and CW+HMB-FA will be administered together at time points describe above. Statistical Analysis Statistical evaluation of performance and biochemical changes will be accomplished using a repeated measures analysis of variance (ANOVA).
Primary Outcome
The 1-RM tests will be performed to assess maximal muscle strength.
Conditions Studied
Interventions
- DIETARY_SUPPLEMENT Placebo
- PROCEDURE cold water immersion
- DIETARY_SUPPLEMENT beta-hydroxy-beta-methylbutyrate free acid (HMB-FA)
Study Locations (1)
Florida
- University of Central Florida, Sport and Exercise Science - Orlando
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 40 participants |
| Start Date | 2012-12 |
| Est. Completion | 2013-04 |
| Phase | NA |
What the finished NCT01793779 record still lists
NCT01793779 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 40 participants, a relatively small participant target, roughly in line with the 38-participant average among 6 other Muscle Damage trials with a reported enrollment target.
The record links to 1 condition, with Muscle Damage appearing as the primary indexed condition, and to 3 interventions - of which Placebo is the first listed.
NCT01793779 reports a single indexed study location in Florida.
Frequently Asked Questions
What is clinical trial NCT01793779 about?
NCT01793779 is a clinical study titled "Comparison of Pre-exercise Beta-hydroxy-beta-methylbutyrate Free Acid (HMB-FA) and Cold Water Therapy for the Attenuation of Muscle Damage and Soreness". Study Objectives 1. Compare beta-hydroxy-beta-methylbutyrate free acid (HMB-FA) to cold water immersion on performance recovery from an acute bout of high intensity resistance exercise. 2. Compare HMB-FA + Cold water immersion to HMB-FA or cold water immersion. 3. Examine the effect of these recove...
What is the current status of trial NCT01793779?
This trial is currently completed. It is a NA study. The enrollment target is 40 participants. The study started on 2012-12. Estimated completion is 2013-04.
What conditions does trial NCT01793779 study?
This clinical trial studies the following conditions: Muscle Damage.
What interventions are being tested in trial NCT01793779?
The interventions under investigation include: Placebo (DIETARY_SUPPLEMENT), cold water immersion (PROCEDURE), beta-hydroxy-beta-methylbutyrate free acid (HMB-FA) (DIETARY_SUPPLEMENT).
Who is sponsoring clinical trial NCT01793779?
This trial is sponsored by Metabolic Technologies, which has 16 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT01793779 being conducted?
This trial has 1 study location across Florida. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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