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NCT01606488 · ClinicalTrials.gov registry record · Phase 4
Effects of Brain Beta-Amyloid on Postoperative Cognition
A Phase 4 study of Postoperative Cognitive Dysfunction, sponsored by University of California, San Francisco.
- Active
- Registry status
- Phase 4
- Development phase
- 66
- Enrollment target
- 1
- Study location
NCT01606488: Active Phase 4 study of Postoperative Cognitive Dysfunction, sponsored by University of California, San Francisco.
NCT01606488 is a Phase 4 study of Postoperative Cognitive Dysfunction that is active but no longer recruiting, run by University of California, San Francisco. The registered enrollment target is 66 participants, below the 185-participant average among 6 other Postoperative Cognitive Dysfunction trials with a reported enrollment target (64% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01606488, a Phase 4 study of Postoperative Cognitive Dysfunction, is active but no longer recruiting, sponsored by University of California, San Francisco.
- ACTIVE NOT RECRUITING
- Registry status
- Phase 4
- Development phase
- 66 participants
- Enrollment target
- 1
- Study location
Study Summary
Postoperative cognitive decline (POCD) affects up to 50% of non-cardiac surgical patients greater than or equal to 65 years of age. This study will test the hypothesis that preoperative presence of brain beta-amyloid plaques in non-demented subjects increases postoperative cognitive decline (POCD) in elderly subjects scheduled for hip or knee replacement. The investigators hypothesize that preoperative beta-amyloid plaques will predict postoperative cognitive decline.
Primary Outcome
Measured using comprehensive neurocognitive test battery
Conditions Studied
Interventions
- OTHER no intervention
- DRUG Florbetapir F 18 (18F-AV-45)
Study Locations (1)
California
- San Francisco VA Medical Center - San Francisco
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 66 participants |
| Start Date | 2012-05 |
| Est. Completion | 2026-06 |
| Phase | Phase 4 |
What the registry record for NCT01606488 still lists
NCT01606488 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 66 participants, a relatively small participant target, below the 185-participant average among 6 other Postoperative Cognitive Dysfunction trials with a reported enrollment target (64% lower).
The record links to 1 condition, with Postoperative Cognitive Dysfunction appearing as the primary indexed condition, and to 2 interventions - of which no intervention is the first listed.
NCT01606488 reports a single indexed study location in California.
Frequently Asked Questions
What is clinical trial NCT01606488 about?
NCT01606488 is a clinical study titled "Effects of Brain Beta-Amyloid on Postoperative Cognition". Postoperative cognitive decline (POCD) affects up to 50% of non-cardiac surgical patients greater than or equal to 65 years of age. This study will test the hypothesis that preoperative presence of brain beta-amyloid plaques in non-demented subjects increases postoperative cognitive decline (POCD) ...
What is the current status of trial NCT01606488?
This trial is currently active not recruiting. It is a Phase 4 study. The enrollment target is 66 participants. The study started on 2012-05. Estimated completion is 2026-06.
What conditions does trial NCT01606488 study?
This clinical trial studies the following conditions: Postoperative Cognitive Dysfunction.
What interventions are being tested in trial NCT01606488?
The interventions under investigation include: no intervention (OTHER), Florbetapir F 18 (18F-AV-45) (DRUG).
Who is sponsoring clinical trial NCT01606488?
This trial is sponsored by University of California, San Francisco, which has 1,713 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT01606488 being conducted?
This trial has 1 study location across California. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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