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NCT01194258 · ClinicalTrials.gov registry record · Phase 2

Safety/Efficacy Study of Subcutaneously Injected Prandial Insulins Compared to Insulin Lispro Alone in Patients With Type 2 Diabetes Mellitus

A Phase 2 study of Diabetes Mellitus Type II, sponsored by Halozyme Therapeutics.

Completed
Registry status
Phase 2
Development phase
132
Enrollment target
20
Study locations

NCT01194258 is a Phase 2 study of Diabetes Mellitus Type II that has completed, run by Halozyme Therapeutics. The registered enrollment target is 132 participants, below the 221-participant average among 7 other Diabetes Mellitus Type II trials with a reported enrollment target (40% lower). The trial reports 20 study locations across 12 states.

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The verdict

NCT01194258, a Phase 2 study of Diabetes Mellitus Type II, has completed, sponsored by Halozyme Therapeutics.

COMPLETED
Registry status
Phase 2
Development phase
132 participants
Enrollment target
20
Study locations

Study Summary

The purpose of the study was to compare Humalog (insulin lispro)-recombinant human hyaluronidase PH20 (rHuPH20) or Novolog (insulin aspart)-rHuPH20 to insulin lispro for the treatment of Type 2 diabetes mellitus (T2DM) in basal-bolus therapy.

Conditions Studied

Interventions

  • DRUG Insulin aspart
  • DRUG Insulin glargine
  • DRUG Insulin lispro
  • DRUG Insulin glulisine
  • DRUG Recombinant human hyaluronidase PH20

Study Locations (20)

California

  • John Muir Physician Network Clinical Research Center - Concord
  • Medical Group of Encino - Encino
  • AMCR Institute, Inc. - Escondido
  • Marin Endocrine Care and Research - Greenbrae
  • Mills-Peninsula Health Services - San Mateo

Florida

  • Center for Diabetes and Endocrine Care - Hollywood
  • Diabetes Research Institute - Miami
  • Baptist Diabetes Associates - Miami

Texas

  • UT Southwestern Medical Center at Dallas - Dallas
  • Texas Diabetes and Endocrinology - Round Rock
  • Cetero Research-San Antonio - San Antonio

Idaho

  • Rocky Mountain Diabetes and Osteoporosis Center - Idaho Falls

Kansas

  • Mid-America Diabetes Associates - Wichita

Louisiana

  • Tulane University Health Sciences Center - New Orleans

Maryland

  • Medstar Research Institute - Hyattsville

Michigan

  • Henry Ford Health System - Detroit

Trial Details

FieldValue
Enrollment Target 132 participants
Start Date 2010-08
Est. Completion 2011-08
Phase Phase 2

Sponsor

Halozyme Therapeutics

31 total trials

What the Registry Record Tells You About NCT01194258

The ClinicalTrials.gov registry entry for NCT01194258 describes a study currently listed as completed, categorized as Phase 2. The registered enrollment target is 132 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 221-participant average among 7 other Diabetes Mellitus Type II trials with a reported enrollment target (40% lower). The listed sponsor is Halozyme Therapeutics, which has 31 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Diabetes Mellitus Type II appearing as the primary indexed condition, and to 5 interventions - of which Insulin aspart is the first listed.

NCT01194258 reports 20 study locations spanning 12 distinct geographic areas - top geographies include California, Florida, Texas.

Frequently Asked Questions

What is clinical trial NCT01194258 about?

NCT01194258 is a clinical study titled "Safety/Efficacy Study of Subcutaneously Injected Prandial Insulins Compared to Insulin Lispro Alone in Patients With Type 2 Diabetes Mellitus". The purpose of the study was to compare Humalog (insulin lispro)-recombinant human hyaluronidase PH20 (rHuPH20) or Novolog (insulin aspart)-rHuPH20 to insulin lispro for the treatment of Type 2 diabetes mellitus (T2DM) in basal-bolus therapy.

What is the current status of trial NCT01194258?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 132 participants. The study started on 2010-08. Estimated completion is 2011-08.

What conditions does trial NCT01194258 study?

This clinical trial studies the following conditions: Diabetes Mellitus Type II.

What interventions are being tested in trial NCT01194258?

The interventions under investigation include: Insulin aspart (DRUG), Insulin glargine (DRUG), Insulin lispro (DRUG), Insulin glulisine (DRUG), Recombinant human hyaluronidase PH20 (DRUG).

Who is sponsoring clinical trial NCT01194258?

This trial is sponsored by Halozyme Therapeutics, which has 31 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT01194258 being conducted?

This trial has 20 study locations across California, Florida, Idaho, Kansas, Louisiana. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Similar trials for Diabetes Mellitus Type II

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.