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NCT01070199 · ClinicalTrials.gov registry record · NA

Effects of Food Form and Fitness on Appetite and Digestion.

A NA study of High and Increasing Contribution of Energy From Beverages in the Diet May Enhance Positive Energy Balance and Weight Gain, sponsored by Purdue University.

Completed
Registry status
NA
Development phase
81
Enrollment target
1
Study location

NCT01070199: Completed NA study of High and Increasing Contribution of Energy From Beverages in the Diet May Enhance Positive Energy Balance and Weight Gain, sponsored by Purdue University.

NCT01070199 is a NA study of High and Increasing Contribution of Energy From Beverages in the Diet May Enhance Positive Energy Balance and Weight Gain that has completed, run by Purdue University. The registered enrollment target is 81 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (94% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT01070199, a NA study of High and Increasing Contribution of Energy From Beverages in the Diet May Enhance Positive Energy Balance and Weight Gain, has completed, sponsored by Purdue University.

COMPLETED
Registry status
NA
Development phase
81 participants
Enrollment target
1
Study location

Study Summary

Energy-yielding fluids induce weaker appetitive and compensatory dietary responses than energy-matched semi-solids or solids. This is problematic because the high and increasing contribution of energy from beverages in the diet may enhance positive energy balance and weight gain. The prevailing view of the overweight/obesity problem is that it stems from a small, sustained positive energy balance. It follows then that only small changes, perhaps manipulations in the rheological characteristics of the diet, will be required to correct the problem. Certain populations that are more prone to weight gain may benefit from such manipulations. Obese individuals have a higher beverage intake and experience greater weight loss with reductions in beverage intake. Further, there is evidence that obese individuals consume more energy after a liquid pre-load than their lean counterparts, yet there is no difference in energy intake after a solid load. In contrast, habitual exercisers have been shown to have an increased accuracy of short-term regulation of food intake at meals following liquid preloads. A better understanding of the mechanisms by which beverages and energy-matched solid food forms elicit differential appetitive and dietary responses in these populations needed. This research will attempt to identify the influence of physical fitness and body fat on the ability to compensate for the energy content of solid and liquid preloads by reduction in energy intake at a subsequent ad libitum meal (i.e., acute compensation) and over the course of the day (i.e., short-term compensation). Furthermore, this study will examine the cognitive contribution to differential responses to energy-matched beverage and solid food forms and the effects of mastication on appetite, GI transit, glycemic response, and selected endocrine responses.

Primary Outcome

Effects of actual and perceived food form on short term energy intake in lean and obese, fit and unfit adults.

Interventions

  • BEHAVIORAL liquid to liquid
  • BEHAVIORAL liquid to solid
  • BEHAVIORAL solid to liquid
  • BEHAVIORAL solid to solid

Study Locations (1)

Indiana

  • Purdue University - West Lafayette

Trial Details

FieldValue
Enrollment Target 81 participants
Start Date 2009-01
Est. Completion 2010-12
Phase NA
Purdue University

141 total trials

What the finished NCT01070199 record still lists

NCT01070199 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 81 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (94% lower).

The record links to 1 condition, with High and Increasing Contribution of Energy From Beverages in the Diet May Enhance Positive Energy Balance and Weight Gain appearing as the primary indexed condition, and to 4 interventions - of which liquid to liquid is the first listed.

NCT01070199 reports a single indexed study location in Indiana.

Frequently Asked Questions

What is clinical trial NCT01070199 about?

NCT01070199 is a clinical study titled "Effects of Food Form and Fitness on Appetite and Digestion.". Energy-yielding fluids induce weaker appetitive and compensatory dietary responses than energy-matched semi-solids or solids. This is problematic because the high and increasing contribution of energy from beverages in the diet may enhance positive energy balance and weight gain. The prevailing view...

What is the current status of trial NCT01070199?

This trial is currently completed. It is a NA study. The enrollment target is 81 participants. The study started on 2009-01. Estimated completion is 2010-12.

What conditions does trial NCT01070199 study?

This clinical trial studies the following conditions: High and Increasing Contribution of Energy From Beverages in the Diet May Enhance Positive Energy Balance and Weight Gain.

What interventions are being tested in trial NCT01070199?

The interventions under investigation include: liquid to liquid (BEHAVIORAL), liquid to solid (BEHAVIORAL), solid to liquid (BEHAVIORAL), solid to solid (BEHAVIORAL).

Who is sponsoring clinical trial NCT01070199?

This trial is sponsored by Purdue University, which has 141 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT01070199 being conducted?

This trial has 1 study location across Indiana. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

How this trial's enrollment target compares

Where NCT01070199's enrollment target sits among peer trials

81 992nd of 2000 higher than 1,007 of 2,000 other NA trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT01070199, the US trial registry maintained by the National Library of Medicine. NCT01070199 (small enrollment · single site footprint · completed) retrieved and formatted by PlainTrial, see methodology.