Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
Cluster Randomized Trial of Hospitals to Assess Impact of Targeted Versus Universal Strategies to Reduce Methicillin-resistant Staphylococcus Aureus (MRSA) in Intensive Care Units (ICUs)
NCT00980980 · View on ClinicalTrials.gov ↗
Study Summary
The Randomized Evaluation of Decolonization versus Universal Clearance to Eliminate MRSA (REDUCE MRSA) Trial is a cluster randomized trial of the comparative effectiveness of three strategies to prevent methicillin-resistant Staphylococcus aureus (MRSA) in intensive care units. The three strategies to be evaluated are: * screening on admission followed by isolation of MRSA+ patients * screening on admission followed by isolation and decolonization of MRSA+ patients * universal decolonization on admission with no screening. The decolonization regimen involves bathing with chlorhexidine plus intra-nasal application of mupirocin. The main outcome will be MRSA+ clinical cultures. The study is a partnership between the CDC, the CDC Prevention Epicenters, and the Hospital Corporation of America.
Conditions Studied
Interventions
- DRUG Chlorhexidine bath and nasal mupirocin
Study Locations (20)
Florida
- Blake Medical Center — Brandenton
- Brandon Hospital — Brandon
- Columbia Hosp Corp S Broward (Westside) — Fort Lauderdale
- Palms West Hospital — Fort Lauderdale
- Plantation General — Fort Lauderdale
- Regional Med Cr Bayonet Point — Hudson
- Largo Medical Center — Largo
- Community Hospital — New Port Richey
- Orange Park Med Ctr — Orange Park
- Fawcett Memorial Hospital — Port Charlotte
- Doctors Hospital of Sarasota — Sarasota
- South Bay Hospital — Sun City Center
- Capital Regional Med Ctr — Tallahassee
Georgia
- Coliseum (Macon) Northside — Macon
- Coliseum Medical Center — Macon
- Cartersville Medical Center — Tucker
Alaska
- Alaska Regional — Anchorage
California
- Los Robles Hosp & Med Ctr — Thousand Oaks
Colorado
- The Medical Center of Aurora — Aurora
Idaho
- Eastern Idaho Reg Med Ctr — Idaho Falls
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 74,256 participants |
| Start Date | 2009-09 |
| Est. Completion | 2011-09 |
| Phase | NA |
Interested in This Trial?
Always speak with your doctor before enrolling in a clinical trial.
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT00980980
The ClinicalTrials.gov registry entry for NCT00980980 describes a study currently listed as completed. It is categorized as NA, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 74,256 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Harvard Pilgrim Health Care, which has 10 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.
The record links to 1 condition, with Methicillin-resistant Staphylococcus Aureus appearing as the primary indexed condition, and to 1 intervention — of which Chlorhexidine bath and nasal mupirocin is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.
Geographic footprint matters for practical reasons: NCT00980980 reports 20 study locations spanning 6 distinct geographic areas — top geographies include Florida, Georgia, Alaska. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.
Frequently Asked Questions
What is clinical trial NCT00980980 about?
NCT00980980 is a clinical study titled "Cluster Randomized Trial of Hospitals to Assess Impact of Targeted Versus Universal Strategies to Reduce Methicillin-resistant Staphylococcus Aureus (MRSA) in Intensive Care Units (ICUs)". The Randomized Evaluation of Decolonization versus Universal Clearance to Eliminate MRSA (REDUCE MRSA) Trial is a cluster randomized trial of the comparative effectiveness of three strategies to prevent methicillin-resistant Staphylococcus aureus (MRSA) in intensive care units. The three strategies ...
What is the current status of trial NCT00980980?
This trial is currently completed. It is a NA study. The enrollment target is 74,256 participants. The study started on 2009-09. Estimated completion is 2011-09.
What conditions does trial NCT00980980 study?
This clinical trial studies the following conditions: Methicillin-resistant Staphylococcus Aureus. These conditions were identified from the trial registry and reflect the primary focus areas of the research.
What interventions are being tested in trial NCT00980980?
The interventions under investigation include: Chlorhexidine bath and nasal mupirocin (DRUG). Each intervention is being evaluated for safety and efficacy as part of this clinical study.
Who is sponsoring clinical trial NCT00980980?
This trial is sponsored by Harvard Pilgrim Health Care, which has 10 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.
Where is trial NCT00980980 being conducted?
This trial has 20 study locations across Alaska, California, Colorado, Florida, Georgia. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
How Clinical Trials Work
Understand phases 1-4, trial design, randomization, and the informed consent process.
Patient Rights in Clinical Trials
Your rights as a participant: consent, withdrawal, privacy, and who to contact.
Finding the Right Clinical Trial
A practical guide to searching trials, understanding eligibility, and evaluating options.
All Guides
Browse our complete library of clinical trial educational resources.
Read our methodology — how this data is sourced, computed, and verified.