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COMPLETED Phase 3

Acute Venous Thrombosis: Thrombus Removal With Adjunctive Catheter-Directed Thrombolysis

NCT00790335 · View on ClinicalTrials.gov ↗

Study Summary

The purpose of this study is to determine if the use of adjunctive Pharmacomechanical Catheter Directed Thrombolysis, which includes the intrathrombus administration of rt-PA--Activase (Alteplase),can prevent the post-thrombotic syndrome(PTS)in patients with symptomatic proximal deep vein thrombosis(DVT)as compared with optimal standard DVT therapy alone.

Interventions

  • DRUG Recombinant tissue plasminogen activator (rt-PA)

Study Locations (20)

Florida

  • Mease Countryside Hospital — Clearwater
  • Baptist Cardiac & Vascular Institute — Miami
  • Florida Hospital — Orlando
  • Florida Hospital-Tampa Division-Pepin Heart Institute and Dr. Kiran C. Patel Research Institute — Tampa

Illinois

  • University of Illinois at Chicago — Chicago
  • Adventist Midwest Health — Hinsdale
  • Southern Illinois University — Springfield
  • Central DuPage Hospital — Winfield

California

  • St. Joseph Hospital — Orange
  • Stanford University Medical Center — Stanford

Connecticut

  • Danbury Hospital — Danbury
  • Eastern Connecticut Hematology and Oncology Associates — Norwich

Arizona

  • Arrowhead Hospital/Phoenix Heart, PLLC — Glendale

Delaware

  • Christiana Care Health Systems — Newark

District of Columbia

  • Georgetown University Hospital — Washington D.C.

Indiana

  • CorVasc — Indianapolis

Trial Details

FieldValue
Enrollment Target 692 participants
Start Date 2009-11
Est. Completion 2017-01
Phase Phase 3

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT00790335

The ClinicalTrials.gov registry entry for NCT00790335 describes a study currently listed as completed. It is categorized as Phase 3, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 692 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Washington University School of Medicine, which has 1,036 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.

The record links to 5 conditions, with Venous Thromboembolism appearing as the primary indexed condition, and to 1 intervention — of which Recombinant tissue plasminogen activator (rt-PA) is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.

Geographic footprint matters for practical reasons: NCT00790335 reports 20 study locations spanning 12 distinct geographic areas — top geographies include Florida, Illinois, California. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.

Frequently Asked Questions

What is clinical trial NCT00790335 about?

NCT00790335 is a clinical study titled "Acute Venous Thrombosis: Thrombus Removal With Adjunctive Catheter-Directed Thrombolysis". The purpose of this study is to determine if the use of adjunctive Pharmacomechanical Catheter Directed Thrombolysis, which includes the intrathrombus administration of rt-PA--Activase (Alteplase),can prevent the post-thrombotic syndrome(PTS)in patients with symptomatic proximal deep vein thrombosis...

What is the current status of trial NCT00790335?

This trial is currently completed. It is a Phase 3 study. The enrollment target is 692 participants. The study started on 2009-11. Estimated completion is 2017-01.

What conditions does trial NCT00790335 study?

This clinical trial studies the following conditions: Venous Thromboembolism, Deep Vein Thrombosis, Venous Thrombosis, Post Thrombotic Syndrome, Postphlebitic Syndrome. These conditions were identified from the trial registry and reflect the primary focus areas of the research.

What interventions are being tested in trial NCT00790335?

The interventions under investigation include: Recombinant tissue plasminogen activator (rt-PA) (DRUG). Each intervention is being evaluated for safety and efficacy as part of this clinical study.

Who is sponsoring clinical trial NCT00790335?

This trial is sponsored by Washington University School of Medicine, which has 1,036 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.

Where is trial NCT00790335 being conducted?

This trial has 20 study locations across Arizona, California, Connecticut, Delaware, District of Columbia. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial