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Multicenter ACL Revision Study (MARS)
NCT00625885 · View on ClinicalTrials.gov ↗
Study Summary
The purpose of this study is to determine the effects of modifiable risk factors on patient-reported quality of life, physical activity levels, and risk of early osteoarthritis following revision anterior cruciate ligament (ACL) reconstruction. The investigators hypothesize that modifiable variables exist at the time of revision ACL reconstruction (e.g., cause of failure, current graft source and type, surgical exposure, and femoral and tibial tunnel position) which will be predictors of patient-reported outcomes.
Conditions Studied
Study Locations (20)
California
- Scripps Memorial Hospital (OrthoCal Healthcare) — La Jolla
- University of California - Los Angeles (UCLA) — Los Angeles
- University of California - San Francisco — San Francisco
Colorado
- Orthopaedic Associates of Aspen and Glenwood — Aspen
- University of Colorado — Boulder
Connecticut
- Connecticut Children's Medical Center — Farmington
- University of Connecticut Health Center — Farmington
Minnesota
- Mayo Clinic — Rochester
- Regions Hospital (Health Partners Research Foundation) — Saint Paul
Florida
- UHZ Sports Medicine Institute — Coral Gables
Idaho
- Intermountain Orthopaedics — Boise
Illinois
- Rush University Medical Center — Chicago
Indiana
- Methodist Sports Medicine Center — Indianapolis
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 1,234 participants |
| Start Date | 2006-03-26 |
| Est. Completion | 2029-08-31 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT00625885
The ClinicalTrials.gov registry entry for NCT00625885 describes a study currently listed as active not recruiting. It is categorized as an unspecified phase, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 1,234 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Vanderbilt University, which has 194 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.
The record links to 1 condition, with Rupture of Anterior Cruciate Ligament appearing as the primary indexed condition, and to 0 interventions. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.
Geographic footprint matters for practical reasons: NCT00625885 reports 20 study locations spanning 15 distinct geographic areas — top geographies include California, Colorado, Connecticut. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.
Frequently Asked Questions
What is clinical trial NCT00625885 about?
NCT00625885 is a clinical study titled "Multicenter ACL Revision Study (MARS)". The purpose of this study is to determine the effects of modifiable risk factors on patient-reported quality of life, physical activity levels, and risk of early osteoarthritis following revision anterior cruciate ligament (ACL) reconstruction. The investigators hypothesize that modifiable variable...
What is the current status of trial NCT00625885?
This trial is currently active not recruiting. The enrollment target is 1,234 participants. The study started on 2006-03-26. Estimated completion is 2029-08-31.
What conditions does trial NCT00625885 study?
This clinical trial studies the following conditions: Rupture of Anterior Cruciate Ligament. These conditions were identified from the trial registry and reflect the primary focus areas of the research.
Who is sponsoring clinical trial NCT00625885?
This trial is sponsored by Vanderbilt University, which has 194 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.
Where is trial NCT00625885 being conducted?
This trial has 20 study locations across California, Colorado, Connecticut, Florida, Idaho. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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