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NCT00390546 · ClinicalTrials.gov registry record · Phase 3

Multicenter Study of Antiarrhythmic Medications for Treatment of Infants With Supraventricular Tachycardia

A Phase 3 study of Supraventricular Tachycardia, sponsored by University of British Columbia.

Completed
Registry status
Phase 3
Development phase
72
Enrollment target
14
Study locations

NCT00390546 is a Phase 3 study of Supraventricular Tachycardia that has completed, run by University of British Columbia. The registered enrollment target is 72 participants, below the 107-participant average among 3 other Supraventricular Tachycardia trials with a reported enrollment target (33% lower). The trial reports 14 study locations across 13 states.

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The verdict

NCT00390546, a Phase 3 study of Supraventricular Tachycardia, has completed, sponsored by University of British Columbia.

COMPLETED
Registry status
Phase 3
Development phase
72 participants
Enrollment target
14
Study locations

Study Summary

This is a randomized, double-blind, multi-centered study to compare 6 months of medical treatment with digoxin or propranolol in infants with SVT Background: SVT is the most common sustained arrhythmia of infancy. Neither digoxin nor propranolol has been evaluated for pediatric use in a controlled trial in the context of SVT, yet both medications are used frequently. Specific aims of the study: To determine whether propranolol and digoxin differ in the: 1. Incidence of recurrent SVT in infants after 6 months of treatment with propranolol or digoxin 2. Time to first recurrence of SVT in infants treated with propranolol or digoxin. 3. Incidence of adverse outcomes in infants treated with propranolol or digoxin.

Interventions

  • DRUG Propranolol
  • DRUG Digoxin

Study Locations (14)

California

  • University of Southern California - Children's Hospital of Los Angeles - Los Angeles
  • Children's Hospital of Orange County - Orange

Missouri

  • The Children's Mercy Hospital - Kansas City

New York

  • Schneider Children's Hospital - New Hyde Park

North Carolina

  • Duke University Medical Center - Durham

Ohio

  • Nationwide Children's Hospital Ohio - Columbus

South Carolina

  • Medical University of Charleston South Carolina - Charleston

Utah

  • Primary Children's Medical Centre - Salt Lake City

Virginia

  • Norfolk Children's Hospital of the King's Daughter's - Norfolk

Trial Details

FieldValue
Enrollment Target 72 participants
Start Date 2006-10
Est. Completion 2011-08
Phase Phase 3

Sponsor

University of British Columbia

18 total trials

What the Registry Record Tells You About NCT00390546

The ClinicalTrials.gov registry entry for NCT00390546 describes a study currently listed as completed, categorized as Phase 3. The registered enrollment target is 72 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 107-participant average among 3 other Supraventricular Tachycardia trials with a reported enrollment target (33% lower). The listed sponsor is University of British Columbia, which has 18 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Supraventricular Tachycardia appearing as the primary indexed condition, and to 2 interventions - of which Propranolol is the first listed.

NCT00390546 reports 14 study locations spanning 13 distinct geographic areas - top geographies include California, Missouri, New York.

Frequently Asked Questions

What is clinical trial NCT00390546 about?

NCT00390546 is a clinical study titled "Multicenter Study of Antiarrhythmic Medications for Treatment of Infants With Supraventricular Tachycardia". This is a randomized, double-blind, multi-centered study to compare 6 months of medical treatment with digoxin or propranolol in infants with SVT Background: SVT is the most common sustained arrhythmia of infancy. Neither digoxin nor propranolol has been evaluated for pediatric use in a controlled t...

What is the current status of trial NCT00390546?

This trial is currently completed. It is a Phase 3 study. The enrollment target is 72 participants. The study started on 2006-10. Estimated completion is 2011-08.

What conditions does trial NCT00390546 study?

This clinical trial studies the following conditions: Supraventricular Tachycardia.

What interventions are being tested in trial NCT00390546?

The interventions under investigation include: Propranolol (DRUG), Digoxin (DRUG).

Who is sponsoring clinical trial NCT00390546?

This trial is sponsored by University of British Columbia, which has 18 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT00390546 being conducted?

This trial has 14 study locations across California, Missouri, New York, North Carolina, Ohio. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

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