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NCT00390546 · ClinicalTrials.gov registry record · Phase 3
Multicenter Study of Antiarrhythmic Medications for Treatment of Infants With Supraventricular Tachycardia
A Phase 3 study of Supraventricular Tachycardia, sponsored by University of British Columbia.
- Completed
- Registry status
- Phase 3
- Development phase
- 72
- Enrollment target
- 14
- Study locations
NCT00390546: Completed Phase 3 study of Supraventricular Tachycardia, sponsored by University of British Columbia.
NCT00390546 is a Phase 3 study of Supraventricular Tachycardia that has completed, run by University of British Columbia. The registered enrollment target is 72 participants, below the 107-participant average among 3 other Supraventricular Tachycardia trials with a reported enrollment target (33% lower). The trial reports 14 study locations across 13 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00390546, a Phase 3 study of Supraventricular Tachycardia, has completed, sponsored by University of British Columbia.
- COMPLETED
- Registry status
- Phase 3
- Development phase
- 72 participants
- Enrollment target
- 14
- Study locations
Study Summary
This is a randomized, double-blind, multi-centered study to compare 6 months of medical treatment with digoxin or propranolol in infants with SVT Background: SVT is the most common sustained arrhythmia of infancy. Neither digoxin nor propranolol has been evaluated for pediatric use in a controlled trial in the context of SVT, yet both medications are used frequently. Specific aims of the study: To determine whether propranolol and digoxin differ in the: 1. Incidence of recurrent SVT in infants after 6 months of treatment with propranolol or digoxin 2. Time to first recurrence of SVT in infants treated with propranolol or digoxin. 3. Incidence of adverse outcomes in infants treated with propranolol or digoxin.
Conditions Studied
Interventions
- DRUG Propranolol
- DRUG Digoxin
Study Locations (14)
California
- University of Southern California - Children's Hospital of Los Angeles - Los Angeles
- Children's Hospital of Orange County - Orange
Missouri
- The Children's Mercy Hospital - Kansas City
New York
- Schneider Children's Hospital - New Hyde Park
North Carolina
- Duke University Medical Center - Durham
Ohio
- Nationwide Children's Hospital Ohio - Columbus
South Carolina
- Medical University of Charleston South Carolina - Charleston
Utah
- Primary Children's Medical Centre - Salt Lake City
Virginia
- Norfolk Children's Hospital of the King's Daughter's - Norfolk
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 72 participants |
| Start Date | 2006-10 |
| Est. Completion | 2011-08 |
| Phase | Phase 3 |
What the finished NCT00390546 record still lists
NCT00390546 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 72 participants, a relatively small participant target, below the 107-participant average among 3 other Supraventricular Tachycardia trials with a reported enrollment target (33% lower).
The record links to 1 condition, with Supraventricular Tachycardia appearing as the primary indexed condition, and to 2 interventions - of which Propranolol is the first listed.
NCT00390546 lists 14 locations in 13 states (California, Missouri, New York).
Frequently Asked Questions
What is clinical trial NCT00390546 about?
NCT00390546 is a clinical study titled "Multicenter Study of Antiarrhythmic Medications for Treatment of Infants With Supraventricular Tachycardia". This is a randomized, double-blind, multi-centered study to compare 6 months of medical treatment with digoxin or propranolol in infants with SVT Background: SVT is the most common sustained arrhythmia of infancy. Neither digoxin nor propranolol has been evaluated for pediatric use in a controlled t...
What is the current status of trial NCT00390546?
This trial is currently completed. It is a Phase 3 study. The enrollment target is 72 participants. The study started on 2006-10. Estimated completion is 2011-08.
What conditions does trial NCT00390546 study?
This clinical trial studies the following conditions: Supraventricular Tachycardia.
What interventions are being tested in trial NCT00390546?
The interventions under investigation include: Propranolol (DRUG), Digoxin (DRUG).
Who is sponsoring clinical trial NCT00390546?
This trial is sponsored by University of British Columbia, which has 18 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT00390546 being conducted?
This trial has 14 study locations across California, Missouri, New York, North Carolina, Ohio. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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