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COMPLETED Phase 2

Cediranib Maleate in Treating Patients With Persistent, Recurrent, or Refractory Advanced Ovarian Epithelial, Peritoneal Cavity, or Fallopian Tube Cancer

NCT00278343 · View on ClinicalTrials.gov ↗

Study Summary

This phase II trial is studying how well cediranib maleate works in treating patients with persistent, recurrent, or refractory advanced ovarian epithelial, peritoneal cavity, or fallopian tube cancer. Cediranib maleate may stop the growth of tumor cells by blocking blood flow to the tumor and by blocking some of the enzymes needed for cell growth.

Interventions

  • OTHER laboratory biomarker analysis
  • DRUG cediranib maleate

Study Locations (20)

Illinois

  • University of Chicago — Chicago
  • Decatur Memorial Hospital — Decatur
  • Evanston Hospital CCOP — Evanston
  • Ingalls Memorial Hospital — Harvey
  • Joliet Oncology-Hematology Associates Limited — Joliet
  • Loyola University Medical Center — Maywood
  • Peoria Gynecologic Oncology — Peoria
  • Oncology/Hematology Associates — Peoria
  • Central Illinois Hematology Oncology Center — Springfield

California

  • City of Hope — Duarte
  • University of Southern California/Norris Cancer Center — Los Angeles
  • City of Hope Medical Group Inc — Pasadena
  • University of California at Davis Cancer Center — Sacramento

Indiana

  • Fort Wayne Medical Oncology and Hematology Inc-Parkview — Fort Wayne
  • Northern Indiana Cancer Research Consortium — South Bend

Michigan

  • University of Michigan Comprehensive Cancer Center — Ann Arbor
  • Oncology Care Associates PLLC — Saint Joseph

Maryland

  • University of Maryland/Greenebaum Cancer Center — Baltimore

Missouri

  • Saint John's Mercy Medical Center — St Louis

Pennsylvania

  • University of Pittsburgh Cancer Institute — Pittsburgh

Trial Details

FieldValue
Enrollment Target 74 participants
Start Date 2006-04
Est. Completion 2018-01-15
Phase Phase 2

Sponsor

National Cancer Institute (NCI)

2,390 total trials

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT00278343

The ClinicalTrials.gov registry entry for NCT00278343 describes a study currently listed as completed. It is categorized as Phase 2, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 74 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is National Cancer Institute (NCI), which has 2,390 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.

The record links to 3 conditions, with Recurrent Ovarian Epithelial Cancer appearing as the primary indexed condition, and to 2 interventions — of which laboratory biomarker analysis is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.

Geographic footprint matters for practical reasons: NCT00278343 reports 20 study locations spanning 7 distinct geographic areas — top geographies include Illinois, California, Indiana. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.

Frequently Asked Questions

What is clinical trial NCT00278343 about?

NCT00278343 is a clinical study titled "Cediranib Maleate in Treating Patients With Persistent, Recurrent, or Refractory Advanced Ovarian Epithelial, Peritoneal Cavity, or Fallopian Tube Cancer". This phase II trial is studying how well cediranib maleate works in treating patients with persistent, recurrent, or refractory advanced ovarian epithelial, peritoneal cavity, or fallopian tube cancer. Cediranib maleate may stop the growth of tumor cells by blocking blood flow to the tumor and by bl...

What is the current status of trial NCT00278343?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 74 participants. The study started on 2006-04. Estimated completion is 2018-01-15.

What conditions does trial NCT00278343 study?

This clinical trial studies the following conditions: Recurrent Ovarian Epithelial Cancer, Recurrent Fallopian Tube Cancer, Recurrent Primary Peritoneal Cavity Cancer. These conditions were identified from the trial registry and reflect the primary focus areas of the research.

What interventions are being tested in trial NCT00278343?

The interventions under investigation include: laboratory biomarker analysis (OTHER), cediranib maleate (DRUG). Each intervention is being evaluated for safety and efficacy as part of this clinical study.

Who is sponsoring clinical trial NCT00278343?

This trial is sponsored by National Cancer Institute (NCI), which has 2,390 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.

Where is trial NCT00278343 being conducted?

This trial has 20 study locations across California, Illinois, Indiana, Maryland, Michigan. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial