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COMPLETED Phase 2

Evaluating The Antitumor Activity Of MEDI-522 With Or Without Dacarbazine In Patients With Metastatic Melanoma

NCT00066196 · View on ClinicalTrials.gov ↗

Study Summary

The primary objectives of this study are: * To explore the antitumor activity of MEDI-522 ± DTIC in patients with metastatic melanoma. * To determine the safety of MEDI-522 ± DTIC in this patient population.

Interventions

  • BIOLOGICAL MEDI--522
  • BIOLOGICAL Integrin + Dacarbazine

Study Locations (20)

California

  • Pacific Shores Medical Group — Long Beach
  • Saint Francis Memorial Hospital — San Francisco
  • Cancer Institute Medical Group — Santa Monica
  • Medical Group of North County — Vista

Indiana

  • Indiana Oncology Hematology Consultants — Indianapolis
  • Indiana University Medical Center — Indianapolis

Missouri

  • Kansas City Oncology & Hematology Group — Kansas City
  • The Melanoma Center of St. Louis — St Louis

New York

  • HemOnc Care, P.C. — Brooklyn
  • Memorial Sloan-Kettering Cancer Center — New York

North Carolina

  • UNC-Chapel Hill — Chapel Hill
  • Blumenthal Cancer Center — Charlotte

Arizona

  • Mayo Clinic Arizona — Scottsdale

Connecticut

  • Yale University School of Medicine — New Haven

Florida

  • University of Miami — Miami

Trial Details

FieldValue
Enrollment Target 110 participants
Start Date 2003-08
Est. Completion 2007-06
Phase Phase 2

Sponsor

MedImmune

55 total trials

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT00066196

The ClinicalTrials.gov registry entry for NCT00066196 describes a study currently listed as completed. It is categorized as Phase 2, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 110 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is MedImmune, which has 55 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.

The record links to 2 conditions, with Melanoma appearing as the primary indexed condition, and to 2 interventions — of which MEDI--522 is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.

Geographic footprint matters for practical reasons: NCT00066196 reports 20 study locations spanning 13 distinct geographic areas — top geographies include California, Indiana, Missouri. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.

Frequently Asked Questions

What is clinical trial NCT00066196 about?

NCT00066196 is a clinical study titled "Evaluating The Antitumor Activity Of MEDI-522 With Or Without Dacarbazine In Patients With Metastatic Melanoma". The primary objectives of this study are: * To explore the antitumor activity of MEDI-522 ± DTIC in patients with metastatic melanoma. * To determine the safety of MEDI-522 ± DTIC in this patient population.

What is the current status of trial NCT00066196?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 110 participants. The study started on 2003-08. Estimated completion is 2007-06.

What conditions does trial NCT00066196 study?

This clinical trial studies the following conditions: Melanoma, Malignant Metastatic Melanoma. These conditions were identified from the trial registry and reflect the primary focus areas of the research.

What interventions are being tested in trial NCT00066196?

The interventions under investigation include: MEDI--522 (BIOLOGICAL), Integrin + Dacarbazine (BIOLOGICAL). Each intervention is being evaluated for safety and efficacy as part of this clinical study.

Who is sponsoring clinical trial NCT00066196?

This trial is sponsored by MedImmune, which has 55 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.

Where is trial NCT00066196 being conducted?

This trial has 20 study locations across Arizona, California, Connecticut, Florida, Georgia. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial