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ClinicalTrials.gov 2 recruiting now early-phase tilt small index

Recurrent Childhood Acute Lymphoblastic Leukemia: early-phase trial registry

2 of 12 indexed Recurrent Childhood Acute Lymphoblastic Leukemia trials are currently recruiting, with more weight in Phase 1-2.

Corpus placement: #1,429 of 28,707 conditions by registered trial count.

12 US clinical trials · 2 currently recruiting · #1,429 of 28,707 conditions by registered trial count

Recurrent Childhood Acute Lymphoblastic Leukemia: 12 US clinical trials tracked, 2 recruiting.

Recurrent Childhood Acute Lymphoblastic Leukemia is the subject of 12 registered US clinical trials on ClinicalTrials.gov, 2 of them currently open to new participants. 2 are in Phase 3-4 (later-stage) and 9 in Phase 1-2 (earlier-stage). The most active sponsor is National Cancer Institute (NCI), running 5 of these trials.

Enrollment posture brief

Registry condition recurrent-childhood-acute-lymphoblastic-leukemia

OPEN 2 | RECR 17% | LATE 2 | EARLY 9 | RANK #1429 | SPON 5

Nearest open-share peer: Acute Renal Failure (17% recruiting · 6 trials)

Acute Myeloid Leukemia in Re41.7%Adenocarcinoma of the Rectum41.7%Recurrent Childhood Acut (th…17%Adherence, Patient16.7%Accelerated Phase Chronic My0%
Open-enrollment share among volume-matched conditions near Recurrent Childhood Acute Lymphoblastic Leukemia

Recurrent Childhood Acute Lymphoblastic Leukemia lists 2 open slots (17% of 12 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Recurrent Childhood Acute Lymphoblastic Leukemia on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Recurrent Childhood Acute Lymphoblastic Leukemia is recruiting below its size-band peers.

    2 of 12 indexed trials (16.7%) are open to enrollment, against a 46.5% average across 27,806 conditions with fewer than 20 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. One sponsor concentrates Recurrent Childhood Acute Lymphoblastic Leukemia research.

    National Cancer Institute (NCI) accounts for 5 of 12 trials (41.7%). 6 distinct sponsors appear on at least one study for this condition label.

  3. Typical Recurrent Childhood Acute Lymphoblastic Leukemia enrolment sits around 70 participants.

    Median target enrolment is 70 among the 12 trials that report a genuine target (sentinel values excluded). 7 of those (58.3%) plan for fewer than 100 participants.

  4. Recurrent Childhood Acute Lymphoblastic Leukemia research is mostly interventional.

    11 interventional and 1 observational studies make up this index (91.7% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 17Phase 22Phase 32

Open and recent trials

12 total, page 1 of 1

RECRUITING Phase 1 65 participants

Ex Vivo Drug Sensitivity Testing and Multi-Omics Profiling

Florida International University

NCT05857969

RECRUITING Phase 1 24 participants

HA-1 T TCR T Cell Immunotherapy for the Treatment of Patients With Relapsed or Refractory Acute Leukemia After Donor Stem Cell Transplant

Fred Hutchinson Cancer Center

NCT03326921

ACTIVE NOT RECRUITING Phase 2 108 participants

Total Marrow and Lymphoid Irradiation and Chemotherapy Before DSCT in Treating Patients With High-Risk ALL or AML

City of Hope Medical Center

NCT02094794

ACTIVE NOT RECRUITING Phase 1 33 participants

Study of CD19/CD22 Chimeric Antigen Receptor (CAR) T Cells in Children and Young Adults w/ Recurrent or Refractory B Cell Malignancies

Stanford University

NCT03241940

COMPLETED 520 participants

DNA Analysis of Tumor Tissue Samples From Young Patients With Acute Lymphoblastic Leukemia

Children's Oncology Group

NCT00897507

COMPLETED Phase 3 220 participants

Combination Chemotherapy With or Without Peripheral Stem Cell Transplant in Treating Children With Acute Lymphoblastic Leukemia

National Cancer Institute (NCI)

NCT00022737

COMPLETED Phase 2 148 participants

506U78 in Treating Patients With Refractory Hematologic Cancer

National Cancer Institute (NCI)

NCT00002970

COMPLETED Phase 1 134 participants

Chemoimmunotherapy With Epratuzumab in Relapsed Acute Lymphoblastic Leukemia (ALL)

Children's Oncology Group

NCT00098839

COMPLETED Phase 1 70 participants

Sorafenib in Treating Young Patients With Relapsed or Refractory Solid Tumors or Leukemia

National Cancer Institute (NCI)

NCT01445080

COMPLETED Phase 1 36 participants

17-N-Allylamino-17-Demethoxygeldanamycin in Treating Young Patients With Relapsed or Refractory Solid Tumors or Leukemia

National Cancer Institute (NCI)

NCT00079404

COMPLETED Phase 3 27 participants

Donor Bone Marrow Transplant With or Without G-CSF in Treating Young Patients With Hematologic Cancer or Other Diseases

Children's Oncology Group

NCT00450450

COMPLETED Phase 1 13 participants

Temsirolimus, Dexamethasone, Mitoxantrone Hydrochloride, Vincristine Sulfate, and Pegaspargase in Treating Young Patients With Relapsed Acute Lymphoblastic Leukemia or Non-Hodgkin Lymphoma

National Cancer Institute (NCI)

NCT01403415

Phase Distribution

PhaseTrial count
Phase 1 7
Phase 2 2
Phase 3 2

Named interventions

Most-linked intervention names on Recurrent Childhood Acute Lymphoblastic Leukemia records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

Laboratory Biomarker Analysis Other
4 trials
therapeutic hydrocortisone Drug
2 trials
allogeneic bone marrow transplantation Procedure
2 trials
cytarabine Drug
2 trials
filgrastim Biological
2 trials
cyclophosphamide Drug
2 trials
epratuzumab Biological
1 trials
L-asparaginase Drug
1 trials

US sites by state

Facility locations filed on Recurrent Childhood Acute Lymphoblastic Leukemia trials. A trial with sites in several states counts in each.

California 9 trials
Indiana 4 trials
Pennsylvania 3 trials
Ohio 3 trials
New York 3 trials
Missouri 3 trials
Michigan 3 trials
Maryland 3 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Recurrent Childhood Acute Lymphoblastic Leukemia page

12 registered trials, 2 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

  • 2 Recurrent Childhood Acute Lymphoblastic Leukemia trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
  • National Cancer Institute (NCI) sponsors the most Recurrent Childhood Acute Lymphoblastic Leukemia trials on record, review their full trial history before evaluating a specific study. See National Cancer Institute (NCI)'s trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Recurrent Childhood Acute Lymphoblastic Leukemia condition card totals 12 registered trials; most-linked intervention Laboratory Biomarker Analysis; top US site state California. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.