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2026 data Public-data reference. official source

Recurrent Childhood Acute Lymphoblastic Leukemia

Open-data reference.

12 US clinical trials · 2 currently recruiting

Active & Recent Trials

RECRUITING Phase 1 65 participants

Ex Vivo Drug Sensitivity Testing and Multi-Omics Profiling

Florida International University

NCT05857969

RECRUITING Phase 1 24 participants

HA-1 T TCR T Cell Immunotherapy for the Treatment of Patients With Relapsed or Refractory Acute Leukemia After Donor Stem Cell Transplant

Fred Hutchinson Cancer Center

NCT03326921

ACTIVE NOT RECRUITING Phase 2 108 participants

Total Marrow and Lymphoid Irradiation and Chemotherapy Before DSCT in Treating Patients With High-Risk ALL or AML

City of Hope Medical Center

NCT02094794

ACTIVE NOT RECRUITING Phase 1 33 participants

Study of CD19/CD22 Chimeric Antigen Receptor (CAR) T Cells in Children and Young Adults w/ Recurrent or Refractory B Cell Malignancies

Stanford University

NCT03241940

COMPLETED 520 participants

DNA Analysis of Tumor Tissue Samples From Young Patients With Acute Lymphoblastic Leukemia

Children's Oncology Group

NCT00897507

COMPLETED Phase 3 220 participants

Combination Chemotherapy With or Without Peripheral Stem Cell Transplant in Treating Children With Acute Lymphoblastic Leukemia

National Cancer Institute (NCI)

NCT00022737

COMPLETED Phase 2 148 participants

506U78 in Treating Patients With Refractory Hematologic Cancer

National Cancer Institute (NCI)

NCT00002970

COMPLETED Phase 1 134 participants

Chemoimmunotherapy With Epratuzumab in Relapsed Acute Lymphoblastic Leukemia (ALL)

Children's Oncology Group

NCT00098839

COMPLETED Phase 1 70 participants

Sorafenib in Treating Young Patients With Relapsed or Refractory Solid Tumors or Leukemia

National Cancer Institute (NCI)

NCT01445080

COMPLETED Phase 1 36 participants

17-N-Allylamino-17-Demethoxygeldanamycin in Treating Young Patients With Relapsed or Refractory Solid Tumors or Leukemia

National Cancer Institute (NCI)

NCT00079404

COMPLETED Phase 3 27 participants

Donor Bone Marrow Transplant With or Without G-CSF in Treating Young Patients With Hematologic Cancer or Other Diseases

Children's Oncology Group

NCT00450450

COMPLETED Phase 1 13 participants

Temsirolimus, Dexamethasone, Mitoxantrone Hydrochloride, Vincristine Sulfate, and Pegaspargase in Treating Young Patients With Relapsed Acute Lymphoblastic Leukemia or Non-Hodgkin Lymphoma

National Cancer Institute (NCI)

NCT01403415

Phase Distribution

PhaseTrial count
Early Phase 1 7
Phase 2 2
Phase 3 2

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Recurrent Childhood Acute Lymphoblastic Leukemia Trial Landscape

ClinicalTrials.gov lists 12 US studies indexed under Recurrent Childhood Acute Lymphoblastic Leukemia, and 2 of those are currently open to recruitment — roughly 17% of the total volume on the registry. That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

The phase distribution for Recurrent Childhood Acute Lymphoblastic Leukemia shows 2 late-stage studies (Phase 3 and Phase 4 combined) alongside 9 earlier-phase entries (Phase 1 through Phase 2). Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

Top sponsor activity for Recurrent Childhood Acute Lymphoblastic Leukemia is led by National Cancer Institute (NCI) with 5 indexed trials, alongside 5 other organizations in the top contributor list. The list on this page surfaces up to 12 of the most relevant recent and active entries, ordered with recruiting studies first so practical options are visible. All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation — eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Recurrent Childhood Acute Lymphoblastic Leukemia?

PlainTrial tracks 12 US clinical trials for Recurrent Childhood Acute Lymphoblastic Leukemia, of which 2 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Recurrent Childhood Acute Lymphoblastic Leukemia?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2024 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

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