Browse All Conditions

Explore 28,964 medical conditions with active and completed U.S. clinical trial data drawn from ClinicalTrials.gov, the U.S. National Institutes of Health public registry. According to ClinicalTrials.gov, the National Institutes of Health public registry maintained by the U.S. National Library of Medicine catalogs more than 500,000 clinical studies across over 220 countries since 1997, with the U.S. Food and Drug Administration Amendments Act (FDAAA) of 2007 requiring registration for most studies of FDA-regulated products. See our methodology for refresh cadence.

PlainTrial's condition directory indexes every disease, disorder, syndrome, and medical condition with at least one clinical study registered on ClinicalTrials.gov. Each entry links to a per-condition profile page showing recruiting trials, completed studies, phase distribution, sponsor mix, and geographic coverage. We use the MeSH-aligned condition names submitted by trial sponsors to the National Library of Medicine, so a condition you find here is the same condition a clinician would search on PubMed or a researcher would tag in a grant application.

Use the alphabetical index to browse the full list, or sort by trial volume to find conditions with the deepest active research pipelines. Conditions with a "Recruiting" count in the third column have at least one trial currently enrolling participants - click through to see locations and eligibility. Conditions with high trial counts but zero recruiting slots usually reflect a maturing pipeline (Phase 3 studies are enrollment-closed) or a condition where standard-of-care has shifted research focus to combination therapies and post-approval surveillance.

The directory is comprehensive but not equally deep across conditions. Rare diseases may show fewer than a handful of trials because patient populations are limited - this is a feature of clinical research, not an indexing gap on our end. Common conditions (cancer subtypes, diabetes, hypertension, depression) show dozens to hundreds of studies because they attract the broadest sponsor investment. Every number on this page comes directly from ClinicalTrials.gov; we do not manually edit counts, and we update from the NLM bulk-export on a regular cadence so what you see reflects the most recent registry state we have ingested.

Breast Cancer1251Healthy1096Obesity1057Prostate Cancer749Depression687Cancer621HIV Infections615Hypertension472Stroke456Non-Small Cell Lung Cancer450
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Treemap Treemap of 10 categories, sized proportional to value. Breast Cancer - 1,251 Breast Cancer 1,251 Healthy - 1,096 Healthy 1,096 Obesity - 1,057 Obesity 1,057 Prostate Cancer - 749 Prostate Cancer 749 Depression - 687 Depression 687 Cancer - 621 Cancer 621 HIV Infections - 615 HIV Infections 615 Hypertension - 472 Hypertension 472 Stroke - 456 Stroke 456 Non-Small Cell Lung Cancer - 450 Non-Small Cell Lu… 450
Condition Trials
Extra Uterine Growth Restriction 1
Extra-axial Tumors 1
Extra-Pancreatic Neuroendocrine Tumor (epNET) 1
Extra-pulmonary Neuroendocrine Carcinoma 1
Extraarticular Distal Radius Malunion 1
Extracellular Vesicles 1
Extracellular Volume Overload 1
Extracorporeal Membrane Oxygenation 6
Extracorporeal Membrane Oxygenation Complication 9
Extracranial Solid Neoplasm 1
Extraction Sites After Removal and Bone Replacement Grafting at Extraction Sockets of Dentally Hopeless Single-rooted Teeth 1
Extraction, Tooth 1
Extragonadal Embryonal Carcinoma 1
Extragonadal Germ Cell Tumor 3
Extragonadal Seminoma 1
Extragonadal Yolk Sac Tumors 1
Extrahepatic Bile Duct Adenocarcinoma, Biliary Type 1
Extrahepatic Bile Duct Cancer 6
Extrahepatic Cholangiocarcinoma 2
Extramammary Paget Disease 3
Extramammary Paget's Disease 3
Extramammary Paget's Disease of Anal Canal (Diagnosis) 1
Extramammary Paget's Disease of Anus (Diagnosis) 1
Extramammary Paget's Disease of Skin 1
Extramammary Paget's Disease of Vagina (Diagnosis) 1
Extramammary Paget's Disease of Vulva (Diagnosis) 1
Extramammary Paget's Disease Vulva Invasive 1
Extramedullary Disease in Multiple Myeloma 2
Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue 12
Extranodal Marginal Zone Lymphoma 1
Extranodal Marginal Zone Lymphoma of Mucosa-Associated Lymphoid Tissue 3
Extranodal Natural Killer/T-Cell Lymphoma, Nasal Type 1
Extranodal NK/T Cell Lymphoma, Nasal Type 1
Extranodal NK/T-cell Lymphoma 1
Extraocular Sebaceous Carcinoma 1
Extrapulmonary Neuroendocrine Carcinoma (EP-NEC) 2
Extrapulmonary Small Cell Cancer 1
Extrapulmonary Small Cell Carcinoma 1
Extrapulmonary Small Cell Neuroendocrine Carcinoma 1
Extrapyramidal Symptoms 1
Extrarenal Rhabdoid Tumor 1
Extraskeletal Myxoid Chondrosarcoma 1
Extraskeletal Osteosarcoma 1
Extravasation 1
Extravasation of Diagnostic and Therapeutic Materials 1
Extreme Longevity 1
Extreme Prematurity 6
Extremely Low Birth Weight 2
Extremely Premature Infant 1
Extremity Amputation 1