Browse All Conditions

Explore 28,964 medical conditions with active and completed U.S. clinical trial data drawn from ClinicalTrials.gov, the U.S. National Institutes of Health public registry. According to ClinicalTrials.gov, the National Institutes of Health public registry maintained by the U.S. National Library of Medicine catalogs more than 500,000 clinical studies across over 220 countries since 1997, with the U.S. Food and Drug Administration Amendments Act (FDAAA) of 2007 requiring registration for most studies of FDA-regulated products. See our methodology for refresh cadence.

PlainTrial's condition directory indexes every disease, disorder, syndrome, and medical condition with at least one clinical study registered on ClinicalTrials.gov. Each entry links to a per-condition profile page showing recruiting trials, completed studies, phase distribution, sponsor mix, and geographic coverage. We use the MeSH-aligned condition names submitted by trial sponsors to the National Library of Medicine, so a condition you find here is the same condition a clinician would search on PubMed or a researcher would tag in a grant application.

Use the alphabetical index to browse the full list, or sort by trial volume to find conditions with the deepest active research pipelines. Conditions with a "Recruiting" count in the third column have at least one trial currently enrolling participants - click through to see locations and eligibility. Conditions with high trial counts but zero recruiting slots usually reflect a maturing pipeline (Phase 3 studies are enrollment-closed) or a condition where standard-of-care has shifted research focus to combination therapies and post-approval surveillance.

The directory is comprehensive but not equally deep across conditions. Rare diseases may show fewer than a handful of trials because patient populations are limited - this is a feature of clinical research, not an indexing gap on our end. Common conditions (cancer subtypes, diabetes, hypertension, depression) show dozens to hundreds of studies because they attract the broadest sponsor investment. Every number on this page comes directly from ClinicalTrials.gov; we do not manually edit counts, and we update from the NLM bulk-export on a regular cadence so what you see reflects the most recent registry state we have ingested.

Breast Cancer1251Healthy1096Obesity1057Prostate Cancer749Depression687Cancer621HIV Infections615Hypertension472Stroke456Non-Small Cell Lung Cancer450
A2832B1103C2954D1173E990F827G777H1716I1113J83K188L1242M2127N1045O826P2857Q24R1694S3019T976U530V511W241X47Y19Z17
Treemap Treemap of 10 categories, sized proportional to value. Breast Cancer - 1,251 Breast Cancer 1,251 Healthy - 1,096 Healthy 1,096 Obesity - 1,057 Obesity 1,057 Prostate Cancer - 749 Prostate Cancer 749 Depression - 687 Depression 687 Cancer - 621 Cancer 621 HIV Infections - 615 HIV Infections 615 Hypertension - 472 Hypertension 472 Stroke - 456 Stroke 456 Non-Small Cell Lung Cancer - 450 Non-Small Cell Lu… 450 Non-Small Cell Lung Cancer - 450 Non-Small Cell Lu… 450
Condition Trials
Education, Professional 1
Educational Activities 3
Educational Attainment 2
Educational Intervention 1
Educational Materials for Genetic Testing 1
Educational Outcomes 1
Educational Problems 9
Educational Support 1
Edwards Syndrome 2
EE 1
EEG 3
EEG With Periodic Abnormalities 1
Effect of Age-related Changes in the Brain on Walking Ability 1
Effect of Food 2
Effect of Food Supplement 1
Effect of Game in Increasing Environmental Health Literacy 1
Effect of Resveratrol on Performance and Recovery 1
Effects of Cerebellar Stimulation on Brain Activation 1
Effects of Chemotherapy 3
Effects of Dexrazoxane on Healthy Human 1
Effects of External Neurostimulation on Cognition 1
Effects of Family History of Alcoholism and Sex on Alcohol Analgesia 1
Effects of GAHT, on Skeletal Muscle in TGD 1
Effects of Vibration 1
Effects of Whole Body Vibration Exercise on Metabolic Systems 1
Effects of; Exertion 2
Efficacy 4
Efficacy, Self 1
Effusion Joint 1
EGF-R Positive Non-Small Cell Lung Cancer 1
EGFR 4
EGFR Activating Mutation 1
EGFR Amplification 1
EGFR Exon 19 Deletion 1
EGFR Exon 19 Deletion Mutation 1
EGFR Exon 20 Insertion Mutations 1
EGFR Exon 20 Mutation 1
EGFR Exon 20 Mutations 2
EGFR Gene Amplification 1
EGFR Gene Mutation 10
EGFR Gene Overexpression 1
EGFR Inhibitor Induced Acneiform Lesions 1
EGFR Inhibitor-associated Rash 2
Egfr L858R 1
EGFR Mutant Advanced Non-small Cell Lung Cancer 1
EGFR Mutated Non-small Cell Lung Cancer Patients 1
EGFR Mutation 2
EGFR Mutation Positive Non-small Cell Lung Cancer 1
EGFR Mutation-Related Tumors 2
EGFR Negative Non-Small Cell Lung Cancer 1